E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach

Iyan Sopyan, Insan Sunan K, Dolih Gozali.

Abstract
Drug encapsulation in liposomes has provided an opportunity to improve therapeutic drugs mainly through changes in biodistribution and targeting of drugs to certain tissues. The role of liposomes as a drug delivery system is to provide drugs in a controlled manner, reduce toxicity, and increase the efficacy of encapsulated drugs. Although liposomes have been widely investigated in the pharmaceutical field, liposomes have problems related to stability, including particles forming aggregates and the occurrence of drug leakage in vesicles during storage. Therefore, physical stability studies are needed to ensure product integrity during storage. A number of methods were obtained to maintain liposome stability including, freeze-drying, modification with chitosan, the addition of surfactants, and incorporation with polymer gel. Therefore, this article is intended to discuss liposome stabilization and various characterization parameters as a benchmark for liposomal stability.

Key words: Liposome, Stability, phospholipid.


 
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How to Cite this Article
Pubmed Style

Iyan Sopyan, Insan Sunan K, Dolih Gozali. A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach. SRP. 2020; 11(6): 555-562. doi:10.31838/srp.2020.6.85


Web Style

Iyan Sopyan, Insan Sunan K, Dolih Gozali. A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach. http://www.sysrevpharm.org//?mno=117010 [Access: June 20, 2020]. doi:10.31838/srp.2020.6.85


AMA (American Medical Association) Style

Iyan Sopyan, Insan Sunan K, Dolih Gozali. A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach. SRP. 2020; 11(6): 555-562. doi:10.31838/srp.2020.6.85



Vancouver/ICMJE Style

Iyan Sopyan, Insan Sunan K, Dolih Gozali. A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach. SRP. (2020), [cited June 20, 2020]; 11(6): 555-562. doi:10.31838/srp.2020.6.85



Harvard Style

Iyan Sopyan, Insan Sunan K, Dolih Gozali (2020) A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach. SRP, 11 (6), 555-562. doi:10.31838/srp.2020.6.85



Turabian Style

Iyan Sopyan, Insan Sunan K, Dolih Gozali. 2020. A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach. Systematic Reviews in Pharmacy, 11 (6), 555-562. doi:10.31838/srp.2020.6.85



Chicago Style

Iyan Sopyan, Insan Sunan K, Dolih Gozali. "A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach." Systematic Reviews in Pharmacy 11 (2020), 555-562. doi:10.31838/srp.2020.6.85



MLA (The Modern Language Association) Style

Iyan Sopyan, Insan Sunan K, Dolih Gozali. "A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach." Systematic Reviews in Pharmacy 11.6 (2020), 555-562. Print. doi:10.31838/srp.2020.6.85



APA (American Psychological Association) Style

Iyan Sopyan, Insan Sunan K, Dolih Gozali (2020) A Review: A Novel of Efforts to Enhance Liposome Stability as Drug Delivery Approach. Systematic Reviews in Pharmacy, 11 (6), 555-562. doi:10.31838/srp.2020.6.85





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