E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad.

Abstract
Background: Among Haemophilus influenzae species, H. influenzae type b commonly causes pneumonia and meningitis in infants, whereas nontypeable H. influenzae commonly causes community-acquired pneumonia in adults.
Methods: We investigated the role of H. influenzae type b as a causative agent of pneumonia among adults; hundred blood and serum samples were collected from adult patients with respiratory tract infection and radiologically confirmed pneumonia but with negative results for routinely suspected organisms causing pneumonia. Complete etiological detection was achieved using enzyme-linked immunosorbent assay for both anti-H. influenzae type b immunoglobulin M and G antibodies and confirmed by polymerase chain reaction.
Results: Seropositivity to anti-H. influenzae type b immunoglobulin G antibodies was observed in 26% pneumonic adult patients, 53.8% of whom also had anti-H. influenzae type b immunoglobulin M antibodies. Confirmatory polymerase chain reaction revealed that all 26 seropositive patients were positive, whereas only 2 of the patients seronegative for both immunoglobulin M and immunoglobulin G antibodies were positive to H. influenzae type b.
Conclusion: These findings indicated that H. influenzae type b is recently being considered as an important etiological agent of community-acquired idiopathic pneumonia in adults in Iraq; this change in the target population represents a demographic change in H. influenzae type b pathogenicity. Therefore, elderly patients must be included in the immunization schedule and therapeutic prophylaxis against H. influenzae type b infection.

Key words: Hib target group; Eastern Mediterranean region; Iraq


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Ghassaq T. Alubaidi
Articles by Sattar Gaber Ajeel
Articles by Dalyia A. Hamoodi
Articles by Ilham Ahmed
Articles by Israa Wajeh
Articles by Enas Saad
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad. Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity. SRP. 2020; 11(6): 672-676. doi:10.31838/srp.2020.6.100


Web Style

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad. Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity. http://www.sysrevpharm.org//?mno=118808 [Access: June 25, 2020]. doi:10.31838/srp.2020.6.100


AMA (American Medical Association) Style

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad. Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity. SRP. 2020; 11(6): 672-676. doi:10.31838/srp.2020.6.100



Vancouver/ICMJE Style

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad. Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity. SRP. (2020), [cited June 25, 2020]; 11(6): 672-676. doi:10.31838/srp.2020.6.100



Harvard Style

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad (2020) Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity. SRP, 11 (6), 672-676. doi:10.31838/srp.2020.6.100



Turabian Style

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad. 2020. Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity. Systematic Reviews in Pharmacy, 11 (6), 672-676. doi:10.31838/srp.2020.6.100



Chicago Style

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad. "Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity." Systematic Reviews in Pharmacy 11 (2020), 672-676. doi:10.31838/srp.2020.6.100



MLA (The Modern Language Association) Style

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad. "Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity." Systematic Reviews in Pharmacy 11.6 (2020), 672-676. Print. doi:10.31838/srp.2020.6.100



APA (American Psychological Association) Style

Ghassaq T. Alubaidi, Sattar Gaber Ajeel, Dalyia A. Hamoodi, Ilham Ahmed, Israa Wajeh, Enas Saad (2020) Detection of Haemophilus influenzae Type b in Pneumonic Adult Patients in Iraq Represents a Demographic Change in Bacterial Pathogenicity. Systematic Reviews in Pharmacy, 11 (6), 672-676. doi:10.31838/srp.2020.6.100





Most Viewed Articles
  • Dental Development between Assisted Reproductive Therapy (Art) and Natural Conceived Children: A Comparative Pilot Study
    Norzaiti Mohd Kenali, Naimah Hasanah Mohd Fathil, Norbasyirah Bohari, Ahmad Faisal Ismail, Roszaman Ramli
    SRP. 2020; 11(1): 01-06
    » Abstract » doi: 10.5530/srp.2020.1.01

  • Psychometric properties of the World Health Organization Quality of life instrument, short form: Validity in the Vietnamese healthcare context
    Trung Quang Vo*, Bao Tran Thuy Tran, Ngan Thuy Nguyen, Tram ThiHuyen Nguyen, Thuy Phan Chung Tran
    SRP. 2020; 11(1): 14-22
    » Abstract » doi: 10.5530/srp.2020.1.03

  • A Prospective Review on Phyto-Pharmacological Aspects of Andrographis paniculata
    Govindraj Akilandeswari, Arumugam Vijaya Anand, Palanisamy Sampathkumar, Puthamohan Vinayaga Moorthi, Basavaraju Preethi
    SRP. 2019; 10(1): 15-19
    » Abstract » doi: 10.5530/srp.2019.1.3

  • A Review of Pharmacoeconomics: the key to “Healthcare for All”
    Hasamnis AA, Patil SS, Shaik Imam, Narendiran K
    SRP. 2019; 10(1): s40-s42
    » Abstract » doi: 10.5530/srp.2019.1s.21

  • Deuterium Depleted Water as an Adjuvant in Treatment of Cancer
    Anton Syroeshkin, Olga Levitskaya, Elena Uspenskaya, Tatiana Pleteneva, Daria Romaykina, Daria Ermakova
    SRP. 2019; 10(1): 112-117
    » Abstract » doi: 10.5530/srp.2019.1.19

  • Most Downloaded
  • Dental Development between Assisted Reproductive Therapy (Art) and Natural Conceived Children: A Comparative Pilot Study
    Norzaiti Mohd Kenali, Naimah Hasanah Mohd Fathil, Norbasyirah Bohari, Ahmad Faisal Ismail, Roszaman Ramli
    SRP. 2020; 11(1): 01-06
    » Abstract » doi: 10.5530/srp.2020.1.01

  • Manilkara zapota (L.) Royen Fruit Peel: A Phytochemical and Pharmacological Review
    Karle Pravin P, Dhawale Shashikant C
    SRP. 2019; 10(1): 11-14
    » Abstract » doi: 0.5530/srp.2019.1.2

  • Pharmacognostic and Phytopharmacological Overview on Bombax ceiba
    Pankaj Haribhau Chaudhary, Mukund Ganeshrao Tawar
    SRP. 2019; 10(1): 20-25
    » Abstract » doi: 10.5530/srp.2019.1.4

  • A Review of Pharmacoeconomics: the key to “Healthcare for All”
    Hasamnis AA, Patil SS, Shaik Imam, Narendiran K
    SRP. 2019; 10(1): s40-s42
    » Abstract » doi: 10.5530/srp.2019.1s.21

  • A Prospective Review on Phyto-Pharmacological Aspects of Andrographis paniculata
    Govindraj Akilandeswari, Arumugam Vijaya Anand, Palanisamy Sampathkumar, Puthamohan Vinayaga Moorthi, Basavaraju Preethi
    SRP. 2019; 10(1): 15-19
    » Abstract » doi: 10.5530/srp.2019.1.3

  • Most Cited Articles