Abstract
Manilkara zapota (L.) Royen fruit is a popular fruit crop commonly cultivated in most of the tropical reasons and used for its nutritional values over the world. Two varieties of the fruit are available, round and elongated. Present
review revealed the scientific information on the phytochemicals and
pharmacological evaluations of Manilkara zapota (L.) Royen fruit peel (MZFP), a juice byproduct often considered as a waste or garbage. MZFP constitutes about 20 % of the fruit. The literature survey postulate that main phenolic compounds are primarily concentrated in the peel portion of
this fruit which includes, flavonoids, tannins, phenolic acids, hydroxybenzoic
acids (p-hydroxybenzoic, gallic and ellagic), flavanols (catechin and epicatechin),
flavonols (quercetin), hydroxycinnamic acids (ferulic, chlorogenic and trans-cinnamic), kaempferol, 5-caffeoyl quinic acid conjugates and lycopene a carotenoid. It is generally accepted that bioactive components can be more efficiently recovered from MZFP by optimizing the extraction condition or efficiency. A widespread assessment of phytochemicals is included while possible mechanisms and phytochemicals involved have been correlated. The curative relevance of these compounds has been mainly evaluated by
in vitro experimentation. Therefore, convincing clinical trials of the bioactive
principles present in MZFP are essential for correct validation of their health benefits.

Key words: Flavonoids, Manilkara zapota (L.) Royen fruit peel, Phenolics, Pharmacological activities.