E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women

Rajuddin Rajuddin*, Rudy Harahap.

Abstract
ABSTRACT
Body Mass Index (BMI) was closely related to the body fat levels that can affect the menstrual cycle. Body fat contains aromatase enzyme which was needed to produce the estradiol and the excess of estradiol will inhibit the pro¬gesterone production. This may result in progesterone deficiency which further affects the mens¬trual cycle regularity and cause infertility. The aim of this study was to determine the correlation between BMI to estradiol and progesterone levels in infertility women. This study was designed as an observational-analytic with a prospective cohort study. The data of infertile women who fulfilled the study criteria were collected from January 2017 up to December 2018 at Rasi Clinic in Banda Aceh. Serum estradiol and pro¬ges¬terone levels were measured using ELISA technique. Statistical analysis was performed using SPSS version 24. Among 56 women with infertility, there were 30 patients with BMI greater than ≥ 25 (53.6%).
BMI ≥ 25 in infertile women was found significantly correlated to estradiol levels (Chi-square test, p = 0.003). In 26 (86.7%) infertile women, BMI ≥ 25 had significantly increased estradiol level (Odds Ratio 1.8). BMI ≥ 25 was found significantly correlated to progesterone levels (Chi-Square test; p = 0.03). In 19 patients (63,3%) infertile women with BMI ≥ 25, the progesterone level was found significantly decreased (Odds Ratio 2.05). There was a significant correlation between BMI ≥ 25 with the increase serum estradiol and decrease progesterone levels in infertile women.

Key words: Body Mass Index, Estradiol, Progesterone, Infertility.


 
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Pubmed Style

Rajuddin Rajuddin, Rudy Harahap. Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women. SRP. 2019; 10(1): 126-130. doi:10.5530/srp.2019.1.22


Web Style

Rajuddin Rajuddin, Rudy Harahap. Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women. http://www.sysrevpharm.org//?mno=302644724 [Access: June 01, 2020]. doi:10.5530/srp.2019.1.22


AMA (American Medical Association) Style

Rajuddin Rajuddin, Rudy Harahap. Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women. SRP. 2019; 10(1): 126-130. doi:10.5530/srp.2019.1.22



Vancouver/ICMJE Style

Rajuddin Rajuddin, Rudy Harahap. Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women. SRP. (2019), [cited June 01, 2020]; 10(1): 126-130. doi:10.5530/srp.2019.1.22



Harvard Style

Rajuddin Rajuddin, Rudy Harahap (2019) Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women. SRP, 10 (1), 126-130. doi:10.5530/srp.2019.1.22



Turabian Style

Rajuddin Rajuddin, Rudy Harahap. 2019. Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women. Systematic Reviews in Pharmacy, 10 (1), 126-130. doi:10.5530/srp.2019.1.22



Chicago Style

Rajuddin Rajuddin, Rudy Harahap. "Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women." Systematic Reviews in Pharmacy 10 (2019), 126-130. doi:10.5530/srp.2019.1.22



MLA (The Modern Language Association) Style

Rajuddin Rajuddin, Rudy Harahap. "Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women." Systematic Reviews in Pharmacy 10.1 (2019), 126-130. Print. doi:10.5530/srp.2019.1.22



APA (American Psychological Association) Style

Rajuddin Rajuddin, Rudy Harahap (2019) Correlation Between Body Mass Index (BMI) to Estradiol and Progesterone Levels in Infertile Women. Systematic Reviews in Pharmacy, 10 (1), 126-130. doi:10.5530/srp.2019.1.22





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