E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam

Xuan Minh Ngo, Tram Thi Huyen Nguyen, Truc Thi Thanh Nguyen, Lam Ngoc Giang Doan, Nhan Thanh Ngo, Truong Vu Lam, Thoai Dang Nguyen*.

Abstract
Background: Health-related quality of life (HRQoL) is an important indicator of treatment outcomes for patients with Parkinsonís disease (PD). Accordingly, this study determined the HRQoL of PD patients in the context of Vietnam and explored whether disease duration and disease stage affect the HRQoL of the Vietnamese subjects.
Methods: The research assessed 268 PD patients whose conditions have had a mean duration of 8.46 years. Among them, 139 (51.87%) additionally suffered from motor fluctuations and/or dyskinesia. The evaluation was conducted using the 39-item Parkinsonís Disease Questionnaire (PDQ-39), which consists of eight dimensions that can be scored from 0 to 100. The higher the score, the worse the QoL of a patient.
Results: The comparison of the groups with and without motor fluctuations showed that the former scored higher in terms of mobility (MOB), activities of daily living (ADL), emotional well-being (EMO), stigma (STI), social support (SOC), and cognition (COG). A trend observed in this work was that high Hoehn and Yahr scores resulted in equally high PDQ-39 scores, except for the EMO and STI dimensions. The patients suffering
from the disease for more than 5 years had worse MOB, ADL, STI, SOC, and COG scores than those of the subjects grappling with PD for ‚ȧ5 years. Conclusion: The PDQ-39 can determine a decrease in the QoL of PD patients, and such reduction is predicted by the occurrence of motor fluctuations.

Key words: Dyskinesia, Fluctuation, HRQoL, Quality of life, QoL, Parkinson, Vietnam.


 
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How to Cite this Article
Pubmed Style

Ngo XM, Nguyen TTH, Nguyen TTT, Doan LNG, Ngo NT, Lam TV, Nguyen TD. Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam. SRP. 2019; 10(2): 8-14. doi:10.5530/srp.2019.2.02


Web Style

Ngo XM, Nguyen TTH, Nguyen TTT, Doan LNG, Ngo NT, Lam TV, Nguyen TD. Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam. http://www.sysrevpharm.org//?mno=302644899 [Access: June 01, 2020]. doi:10.5530/srp.2019.2.02


AMA (American Medical Association) Style

Ngo XM, Nguyen TTH, Nguyen TTT, Doan LNG, Ngo NT, Lam TV, Nguyen TD. Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam. SRP. 2019; 10(2): 8-14. doi:10.5530/srp.2019.2.02



Vancouver/ICMJE Style

Ngo XM, Nguyen TTH, Nguyen TTT, Doan LNG, Ngo NT, Lam TV, Nguyen TD. Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam. SRP. (2019), [cited June 01, 2020]; 10(2): 8-14. doi:10.5530/srp.2019.2.02



Harvard Style

Ngo, X. M., Nguyen, . T. T. H., Nguyen, . T. T. T., Doan, . L. N. G., Ngo, . N. T., Lam, . T. V. & Nguyen, . T. D. (2019) Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam. SRP, 10 (2), 8-14. doi:10.5530/srp.2019.2.02



Turabian Style

Ngo, Xuan Minh, Tram Thi Huyen Nguyen, Truc Thi Thanh Nguyen, Lam Ngoc Giang Doan, Nhan Thanh Ngo, Truong Vu Lam, and Thoai Dang Nguyen. 2019. Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam. Systematic Reviews in Pharmacy, 10 (2), 8-14. doi:10.5530/srp.2019.2.02



Chicago Style

Ngo, Xuan Minh, Tram Thi Huyen Nguyen, Truc Thi Thanh Nguyen, Lam Ngoc Giang Doan, Nhan Thanh Ngo, Truong Vu Lam, and Thoai Dang Nguyen. "Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam." Systematic Reviews in Pharmacy 10 (2019), 8-14. doi:10.5530/srp.2019.2.02



MLA (The Modern Language Association) Style

Ngo, Xuan Minh, Tram Thi Huyen Nguyen, Truc Thi Thanh Nguyen, Lam Ngoc Giang Doan, Nhan Thanh Ngo, Truong Vu Lam, and Thoai Dang Nguyen. "Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam." Systematic Reviews in Pharmacy 10.2 (2019), 8-14. Print. doi:10.5530/srp.2019.2.02



APA (American Psychological Association) Style

Ngo, X. M., Nguyen, . T. T. H., Nguyen, . T. T. T., Doan, . L. N. G., Ngo, . N. T., Lam, . T. V. & Nguyen, . T. D. (2019) Quality of life among patients with Parkinsonís disease: A cross-sectional study in Vietnam. Systematic Reviews in Pharmacy, 10 (2), 8-14. doi:10.5530/srp.2019.2.02





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