E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice

Nahidah Ibrahim Hammadi, Marwan Mahmood Saleh, Raghad Aadel Ibrahim, Eman Naji Saleh.

Abstract
Spirulina is unique among blue-green algae, it has a long history of safe use, Spirulina have many benefits for many body systems. The present study deals with the effect of Spirulina Platens that purified from DXN company in Malaysia on the function and histological changes of liver in mice. This was achieved by evaluating the following: 20 mice were divided in to four groups each group has 5 mice: treated groups G1, G2 and G3 (200ug/kg, 100 ug/kg and 50 ug/kg) respectively were orally administration with spirulina compare with control group was administrated normal salin . Body weighs, blood test (haematology and biochenmical parameters) and histological evaluations were studied. The results were showed a significant (p< 0.05) increases in Hb, MCHC, MCV WBC and lymphocytes, levels in G1 compare with control. Other hand the results of liver biomarkers such as cholesterol, Triglycerides , AST showed decreased in G1. a significant difference (p< 0.05) in B.W in all groups compare with control. In conculsion. The results of the study reflected that Spirulina was a valuable and more effective in treatment and It seems deserves attention as potential natural supplemented.

Key words: spirulina , diet supplement, liver, biochemical


 
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How to Cite this Article
Pubmed Style

Hammadi NI, Saleh MM, Ibrahim RA, Saleh EN. Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice. SRP. 2020; 11(1): 80-86. doi:10.5530/srp.2020.1.13


Web Style

Hammadi NI, Saleh MM, Ibrahim RA, Saleh EN. Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice. http://www.sysrevpharm.org//?mno=302645241 [Access: February 23, 2020]. doi:10.5530/srp.2020.1.13


AMA (American Medical Association) Style

Hammadi NI, Saleh MM, Ibrahim RA, Saleh EN. Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice. SRP. 2020; 11(1): 80-86. doi:10.5530/srp.2020.1.13



Vancouver/ICMJE Style

Hammadi NI, Saleh MM, Ibrahim RA, Saleh EN. Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice. SRP. (2020), [cited February 23, 2020]; 11(1): 80-86. doi:10.5530/srp.2020.1.13



Harvard Style

Hammadi, N. I., Saleh, . M. M., Ibrahim, . R. A. & Saleh, . E. N. (2020) Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice. SRP, 11 (1), 80-86. doi:10.5530/srp.2020.1.13



Turabian Style

Hammadi, Nahidah Ibrahim, Marwan Mahmood Saleh, Raghad Aadel Ibrahim, and Eman Naji Saleh. 2020. Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice. Systematic Reviews in Pharmacy, 11 (1), 80-86. doi:10.5530/srp.2020.1.13



Chicago Style

Hammadi, Nahidah Ibrahim, Marwan Mahmood Saleh, Raghad Aadel Ibrahim, and Eman Naji Saleh. "Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice." Systematic Reviews in Pharmacy 11 (2020), 80-86. doi:10.5530/srp.2020.1.13



MLA (The Modern Language Association) Style

Hammadi, Nahidah Ibrahim, Marwan Mahmood Saleh, Raghad Aadel Ibrahim, and Eman Naji Saleh. "Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice." Systematic Reviews in Pharmacy 11.1 (2020), 80-86. Print. doi:10.5530/srp.2020.1.13



APA (American Psychological Association) Style

Hammadi, N. I., Saleh, . M. M., Ibrahim, . R. A. & Saleh, . E. N. (2020) Effect of Dietary Supplement with Spirulina Platens on the Functional and Histological Changes in the Liver of Mice. Systematic Reviews in Pharmacy, 11 (1), 80-86. doi:10.5530/srp.2020.1.13





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