E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Assessment of Liver Enzymes and Cytokines in Typhoid Fever

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa.

Abstract
Typhoid fever is one of the most prevalent diseases in developing countries with high significant morbidity and mortality rates. In this study 120 patients with typhoid fever (males and females) aged 20 to 50 years, and 60 healthy individuals in the same age as a control group, from Al-Sader teaching medical city in Najaf/Iraq, from 1stMarch 2019 to the end of September2019 to assess their liver function and pro-inflammatory cytokines (IL-6 andIL-8)levels in their serum. Mean value to serum levels of liver enzymes: alkaline phosphatase (ALP), alanine transaminases (ALT) and aspartate transaminases (AST) were (130±9.8IU/l; 31.4±5.9IU/l; 26.8±4.2IU/l), respectively in Typhoid fever patients (P<.05 for each). Patients also showed significant increase in the concentration of IL–6 (157±5.2pg/ml), IL–8 (136±7.1pg/ml), and C-reactive protein (CRP) 41±3.4 mg/l (P<0.001 for each) compared to healthy subjects 40±6.3 pg/ml; 37±5.9 pg/ml and 9±2.2 mg/l, respectively (P<.001).

Key words: Typhoid fever, Liver enzymes, IL-6, IL-8, C-reactive protein.


 
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How to Cite this Article
Pubmed Style

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa. Assessment of Liver Enzymes and Cytokines in Typhoid Fever. SRP. 2020; 11(3): 297-300. doi:10.5530/srp.2020.3.34


Web Style

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa. Assessment of Liver Enzymes and Cytokines in Typhoid Fever. http://www.sysrevpharm.org//?mno=92914 [Access: June 01, 2020]. doi:10.5530/srp.2020.3.34


AMA (American Medical Association) Style

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa. Assessment of Liver Enzymes and Cytokines in Typhoid Fever. SRP. 2020; 11(3): 297-300. doi:10.5530/srp.2020.3.34



Vancouver/ICMJE Style

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa. Assessment of Liver Enzymes and Cytokines in Typhoid Fever. SRP. (2020), [cited June 01, 2020]; 11(3): 297-300. doi:10.5530/srp.2020.3.34



Harvard Style

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa (2020) Assessment of Liver Enzymes and Cytokines in Typhoid Fever. SRP, 11 (3), 297-300. doi:10.5530/srp.2020.3.34



Turabian Style

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa. 2020. Assessment of Liver Enzymes and Cytokines in Typhoid Fever. Systematic Reviews in Pharmacy, 11 (3), 297-300. doi:10.5530/srp.2020.3.34



Chicago Style

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa. "Assessment of Liver Enzymes and Cytokines in Typhoid Fever." Systematic Reviews in Pharmacy 11 (2020), 297-300. doi:10.5530/srp.2020.3.34



MLA (The Modern Language Association) Style

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa. "Assessment of Liver Enzymes and Cytokines in Typhoid Fever." Systematic Reviews in Pharmacy 11.3 (2020), 297-300. Print. doi:10.5530/srp.2020.3.34



APA (American Psychological Association) Style

Najlaa Abdulameer Ali Al-Dahhan, Bayan Jebur Hussein, Issa Hasan Issa (2020) Assessment of Liver Enzymes and Cytokines in Typhoid Fever. Systematic Reviews in Pharmacy, 11 (3), 297-300. doi:10.5530/srp.2020.3.34





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