E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital

Maria S Ganggur, Sony Wibisono, Musofa Rusli.

Abstract
The increased cortisol is significantly correlated with HIV mortality. The objective of this study was to analyze the correlation between serum cortisol levels and CD4 counts in treatment-naļve patients with HIV/AIDS infection. This was an analytical cross-sectional study. Total serum cortisol levels were measured by ADVIA Centaur® using chemiluminescence immunoassay and CD4 counts were measured by flow cytometry technique using BD FACS Count CD4 reagants®. Among 56 samples of treatment-naļve patients with HIV/AIDS infection, the mean age was 34.3 ± 9 years and they were predominantly male. Mean total cortisol levels was 18.88 ± 9.90 µg/dL, and 32.1% of samples had total cortisol levels of >22.4 µg/dL. As much as 67.9% of the samples presented CD4 counts lower than 200 cells/mm3. There was a significant moderate negative correlation between total cortisol levels and CD4 counts (r = -0.467, p<0.001).Total cortisol levels were negatively correlated with CD4 counts. The higher the total cortisol levels of HIV/AIDS-positive patients, the lower the CD4 counts.

Key words: cortisol, CD4, HIV/AIDS


 
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How to Cite this Article
Pubmed Style

Maria S Ganggur, Sony Wibisono, Musofa Rusli. Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital. SRP. 2020; 11(3): 596-602. doi:10.31838/srp.2020.3.78


Web Style

Maria S Ganggur, Sony Wibisono, Musofa Rusli. Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital. http://www.sysrevpharm.org//?mno=96007 [Access: May 31, 2020]. doi:10.31838/srp.2020.3.78


AMA (American Medical Association) Style

Maria S Ganggur, Sony Wibisono, Musofa Rusli. Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital. SRP. 2020; 11(3): 596-602. doi:10.31838/srp.2020.3.78



Vancouver/ICMJE Style

Maria S Ganggur, Sony Wibisono, Musofa Rusli. Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital. SRP. (2020), [cited May 31, 2020]; 11(3): 596-602. doi:10.31838/srp.2020.3.78



Harvard Style

Maria S Ganggur, Sony Wibisono, Musofa Rusli (2020) Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital. SRP, 11 (3), 596-602. doi:10.31838/srp.2020.3.78



Turabian Style

Maria S Ganggur, Sony Wibisono, Musofa Rusli. 2020. Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital. Systematic Reviews in Pharmacy, 11 (3), 596-602. doi:10.31838/srp.2020.3.78



Chicago Style

Maria S Ganggur, Sony Wibisono, Musofa Rusli. "Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital." Systematic Reviews in Pharmacy 11 (2020), 596-602. doi:10.31838/srp.2020.3.78



MLA (The Modern Language Association) Style

Maria S Ganggur, Sony Wibisono, Musofa Rusli. "Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital." Systematic Reviews in Pharmacy 11.3 (2020), 596-602. Print. doi:10.31838/srp.2020.3.78



APA (American Psychological Association) Style

Maria S Ganggur, Sony Wibisono, Musofa Rusli (2020) Correlation between Serum Cortisol Levels and Cd4 Counts in Treatment-Naļve Patients with HIV/AIDS Infection at Tertiary Hospital. Systematic Reviews in Pharmacy, 11 (3), 596-602. doi:10.31838/srp.2020.3.78