E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto.

Abstract
The treatment HIV/AIDS uses ARVs, one of which is FDC tenofovir. FDC tenofovir is associated with changes in kidney function. This study aimed to determine changes in serum creatinine levels and eGFR in nave HIV patients who received FDC tenofovir therapy for 3 months. This prospective longitudinal study included nave HIV patients who received tenofovir. Serum creatinine levels and eGFR was measured before administration of tenofovir and after 3 months administration of tenofovir. Among 30 patients, the subject consisted 20 (66,7%) males and 10 (33.3%) females. The median age was 37 with range 17-57 years. The mean serum creatinine before tenofovir treatment 0.89 0.25 mg/dL and after 3 months treatment mean SD 0.92 0.28 mg/dL. The mean eGFR before administration of tenofovir treatment 89.37 33.54 ml/min/1.73m2 and after 3 months the mean SD 88.31 33.56 ml/min/1.73m2. There were no significant changes in serum creatinine and eGFR after 3 months administration of tenofovir (p = 0.441; p = 0.771, respectively). Serum creatinine and eGFR were not change after administration of tenofovir in nave HIV patients.

Key words: HIV, tenofovir, serum creatinine, eGFR


 
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How to Cite this Article
Pubmed Style

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto. Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months. SRP. 2020; 11(3): 608-611. doi:10.31838/srp.2020.3.80


Web Style

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto. Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months. http://www.sysrevpharm.org//?mno=96025 [Access: June 01, 2020]. doi:10.31838/srp.2020.3.80


AMA (American Medical Association) Style

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto. Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months. SRP. 2020; 11(3): 608-611. doi:10.31838/srp.2020.3.80



Vancouver/ICMJE Style

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto. Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months. SRP. (2020), [cited June 01, 2020]; 11(3): 608-611. doi:10.31838/srp.2020.3.80



Harvard Style

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto (2020) Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months. SRP, 11 (3), 608-611. doi:10.31838/srp.2020.3.80



Turabian Style

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto. 2020. Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months. Systematic Reviews in Pharmacy, 11 (3), 608-611. doi:10.31838/srp.2020.3.80



Chicago Style

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto. "Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months." Systematic Reviews in Pharmacy 11 (2020), 608-611. doi:10.31838/srp.2020.3.80



MLA (The Modern Language Association) Style

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto. "Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months." Systematic Reviews in Pharmacy 11.3 (2020), 608-611. Print. doi:10.31838/srp.2020.3.80



APA (American Psychological Association) Style

Ridwan Prasetyo, Usman Hadi, Muhammad Vitanata Arfijanto (2020) Changes in Estimated Glomerular Filtration Rate in Naive HIV Patients with Fixed Drugs Combination Tenofovir Treatment in First 3 Months. Systematic Reviews in Pharmacy, 11 (3), 608-611. doi:10.31838/srp.2020.3.80