E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono.

Abstract
Double lumen catheter is a known risk factor for Staphylococcus aureus infection and bacteraemia in haemodialysis patients. The objective of this study was to determine the effectiveness of topical 2% mupirocin cream in lowering the growth of the biofilm at the Haemodialysis Installation of Dr. Soetomo Hospital Surabaya. Our research was an analytical quasi-experimental which subject divided into 2 groups equally, control and mupirocin group. Biofilms catheter was examined by tube test method with a nephelometer. Positive biofilm results if ≥0.36 MF, negative if >0.36 MF. Our research was obtained men (37%) and women (63%) with median age 51.3 (20-73 years). The mean duration of catheter insertion was longer in control than in the mupirocin group, 65.16 and 49, respectively (p = 0.005). There were positive biofilm growth results in both groups, 8 subjects (42%) in control group and 3 subjects (16%) in the mupirocin group, respectively. There was significant differences in the growth of biofilm between the two groups (p = 0.036; rd = 26%). Topical 2% mupirocin cream applied to the exit site CDL significantly reduced the biofilm growth in haemodialysis patients.

Key words: Haemodialysis, double lumen catheter, CDL.


 
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How to Cite this Article
Pubmed Style

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono. The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients. SRP. 2020; 11(3): 612-617. doi:10.31838/srp.2020.3.81


Web Style

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono. The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients. http://www.sysrevpharm.org//?mno=96033 [Access: June 01, 2020]. doi:10.31838/srp.2020.3.81


AMA (American Medical Association) Style

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono. The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients. SRP. 2020; 11(3): 612-617. doi:10.31838/srp.2020.3.81



Vancouver/ICMJE Style

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono. The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients. SRP. (2020), [cited June 01, 2020]; 11(3): 612-617. doi:10.31838/srp.2020.3.81



Harvard Style

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono (2020) The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients. SRP, 11 (3), 612-617. doi:10.31838/srp.2020.3.81



Turabian Style

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono. 2020. The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients. Systematic Reviews in Pharmacy, 11 (3), 612-617. doi:10.31838/srp.2020.3.81



Chicago Style

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono. "The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients." Systematic Reviews in Pharmacy 11 (2020), 612-617. doi:10.31838/srp.2020.3.81



MLA (The Modern Language Association) Style

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono. "The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients." Systematic Reviews in Pharmacy 11.3 (2020), 612-617. Print. doi:10.31838/srp.2020.3.81



APA (American Psychological Association) Style

Astriyani Dyah Febriyanti, Aditiawardana, Widodo, Lindawati Alimsardjono (2020) The Effect of 2% Topical Mupirocin Cream on Biofilm Growth in Double Lumen Catheters in Hemodialysis Patients. Systematic Reviews in Pharmacy, 11 (3), 612-617. doi:10.31838/srp.2020.3.81