Implantable Drug Delivery Systems: An Overview

Systematic Reviews in Pharmacy,2011,2,2,91-95.
Published:Jan, 2011
Type:Review Article

Implantable Drug Delivery Systems: An Overview

Rajgor N, Patel M1, Bhaskar VH

Department of Pharmaceutics, M. P. Patel College of Pharmacy, Kheda, 1Nootan Pharmacy College, S. P. Sahkar Vidhyadham, Gujarat, India

Abstract:

Controlled drug through diffusion and activation-based drug delivery devices have become commercially feasible due to converging technologies and regulatory accommodation. Combination products constructed using implantable technology offer revolutionary opportunities to address unmet medical needs related to dosing. These products have the potential to completely control drug release, meeting requirements for on-demand pulsatile or adjustable continuous administration for extended periods. Implantable technologies, materials science, data management, and biological science have significantly developed in recent years, providing a multidisciplinary foundation for developing integrated therapeutic systems. If smallscale biosensor and drug reservoir units are combined and implanted, a wireless integrated system can regulate drug release, receive sensor feedback, and transmit updates. The tools such as microfabrication technology, information science, and systems biology are being combined to design increasingly sophisticated drug delivery systems that promise to significantly improve medical care.