Invasomes-novel Vesicular Carriers for Enhanced Skin Permeation

Systematic Reviews in Pharmacy,2013,4,1,26-30.
Published:Jan, 2013
Type:Review Article

Invasomes-novel Vesicular Carriers for Enhanced Skin Permeation

P. K. Lakshmi, B. Kalpana, D. Prasanthi

Department of Pharmaceutics, G. Pulla Reddy College of Pharmacy, Affiliated to Osmania University, Hyderabad, Andhra Pradesh, India


Invasomes are the liposomal vesicles embodying small amounts of ethanol and terpenes or terpene mixtures, which act as potential carriers with increased skin penetration. Invasomes have higher penetration rate through the skin as compared to liposomes and ethosomes. Invasomes provide a number of advantages including improving the drug’s efficacy, enhancing patient compliance and comfort. This article reviews various aspects of invasomes including their preparation, characterization, potential advantages in drug delivery. Enhanced delivery of drugs through the skin and cellular membranes by means of an invasomal carrier opens numerous challenges and opportunities for research and future development of novel improved therapies.