E-ISSN 0976-2779 | ISSN 0975-8453
 

Review Article 


Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman.

Abstract
CONTEXT: The study indicated to the biological effectiveness of the compound is Ethyl 6-methyl-2-oxo-4- (2-thienyl) -1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC), as antibacterial which is one of the six compounds extracted from truffles. A number of organic solvents have been used as CH3OH, C2H5OH, CHCl3, C4H8O2, and n-C6H14. The highest percentage of the extract was obtained in the extraction process when using methanol alcohol and the lowest percentage when using chloroform. OBJECTIVE: The biological efficacy of (EMOTTC) was investigated against different types of bacteria by taking higher Concentration of this compound and the lowest concentration of the compound. MATERIALS AND METHODS: The purpose of the manuscript was to study bacterial inhibitory activity using MacConkey Agar as an agricultural medium. (EMOTTC) showed excellent bioavailability against different types of Gram-positive and positive bacteria. The EMOTTC compound has a strong effect on pathogenic bacteria, especially Staphylococcus aureus, Haemophilus influenzae, and Pseudomonas aeruginosa, which indicates that this compound can have multiple drugs uses as an alternative to antibiotics and sterilizers. RESULTS: Using the GC-Mas Spectrum technique, all the bio-organic compounds were diagnosis in the organic layer of the extract, then several methods were performed to determine the type and concentration of each organic compound alone. Spectroscopy of (EMOTTC) was studied, and its biological activity against Gram-positive and Positive bacteria was studied. CONCLUSIONS: Six compounds were detected in Truffle extraction by GC-Mas technology. The same technique demonstrated the ability to isolate (EMOTTC) using different solvents and the effect of this biologically active compound was studied against three Types of bacteria that cause eye infections and ophthalmia.

Key words: Truffles extract, EMOTTC phytochemical extracts, antibacterial activity


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Rana D. S. ALkamil
Articles by Dawood CH. Al-Bahadily
Articles by Rasool Chaloob
Articles by Falah Hassan Shari
Articles by H. N. K. AL-Salman
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman. Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria . SRP. 2020; 11(12): 78-87. doi:10.31838/srp.2020.12.13


Web Style

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman. Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria . http://www.sysrevpharm.org//?mno=129981 [Access: August 30, 2020]. doi:10.31838/srp.2020.12.13


AMA (American Medical Association) Style

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman. Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria . SRP. 2020; 11(12): 78-87. doi:10.31838/srp.2020.12.13



Vancouver/ICMJE Style

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman. Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria . SRP. (2020), [cited August 30, 2020]; 11(12): 78-87. doi:10.31838/srp.2020.12.13



Harvard Style

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman (2020) Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria . SRP, 11 (12), 78-87. doi:10.31838/srp.2020.12.13



Turabian Style

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman. 2020. Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria . Systematic Reviews in Pharmacy, 11 (12), 78-87. doi:10.31838/srp.2020.12.13



Chicago Style

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman. "Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria ." Systematic Reviews in Pharmacy 11 (2020), 78-87. doi:10.31838/srp.2020.12.13



MLA (The Modern Language Association) Style

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman. "Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria ." Systematic Reviews in Pharmacy 11.12 (2020), 78-87. Print. doi:10.31838/srp.2020.12.13



APA (American Psychological Association) Style

Rana D. S. ALkamil, Dawood CH. Al-Bahadily, Rasool Chaloob, Falah Hassan Shari, H. N. K. AL-Salman (2020) Estimation of Truffles extracts and study the biological efficacy of Ethyl 6-methyl-2-oxo-4-(2-thienyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (EMOTTC) as one of the extracts against ophthalmic bacteria . Systematic Reviews in Pharmacy, 11 (12), 78-87. doi:10.31838/srp.2020.12.13





Most Viewed Articles
  • Dental Development between Assisted Reproductive Therapy (Art) and Natural Conceived Children: A Comparative Pilot Study
    Norzaiti Mohd Kenali, Naimah Hasanah Mohd Fathil, Norbasyirah Bohari, Ahmad Faisal Ismail, Roszaman Ramli
    SRP. 2020; 11(1): 01-06
    » Abstract » doi: 10.5530/srp.2020.1.01

  • Psychometric properties of the World Health Organization Quality of life instrument, short form: Validity in the Vietnamese healthcare context
    Trung Quang Vo*, Bao Tran Thuy Tran, Ngan Thuy Nguyen, Tram ThiHuyen Nguyen, Thuy Phan Chung Tran
    SRP. 2020; 11(1): 14-22
    » Abstract » doi: 10.5530/srp.2020.1.03

  • A Prospective Review on Phyto-Pharmacological Aspects of Andrographis paniculata
    Govindraj Akilandeswari, Arumugam Vijaya Anand, Palanisamy Sampathkumar, Puthamohan Vinayaga Moorthi, Basavaraju Preethi
    SRP. 2019; 10(1): 15-19
    » Abstract » doi: 10.5530/srp.2019.1.3

  • A Review of Pharmacoeconomics: the key to “Healthcare for All”
    Hasamnis AA, Patil SS, Shaik Imam, Narendiran K
    SRP. 2019; 10(1): s40-s42
    » Abstract » doi: 10.5530/srp.2019.1s.21

  • Deuterium Depleted Water as an Adjuvant in Treatment of Cancer
    Anton Syroeshkin, Olga Levitskaya, Elena Uspenskaya, Tatiana Pleteneva, Daria Romaykina, Daria Ermakova
    SRP. 2019; 10(1): 112-117
    » Abstract » doi: 10.5530/srp.2019.1.19

  • Most Downloaded
  • Dental Development between Assisted Reproductive Therapy (Art) and Natural Conceived Children: A Comparative Pilot Study
    Norzaiti Mohd Kenali, Naimah Hasanah Mohd Fathil, Norbasyirah Bohari, Ahmad Faisal Ismail, Roszaman Ramli
    SRP. 2020; 11(1): 01-06
    » Abstract » doi: 10.5530/srp.2020.1.01

  • Manilkara zapota (L.) Royen Fruit Peel: A Phytochemical and Pharmacological Review
    Karle Pravin P, Dhawale Shashikant C
    SRP. 2019; 10(1): 11-14
    » Abstract » doi: 0.5530/srp.2019.1.2

  • Pharmacognostic and Phytopharmacological Overview on Bombax ceiba
    Pankaj Haribhau Chaudhary, Mukund Ganeshrao Tawar
    SRP. 2019; 10(1): 20-25
    » Abstract » doi: 10.5530/srp.2019.1.4

  • A Review of Pharmacoeconomics: the key to “Healthcare for All”
    Hasamnis AA, Patil SS, Shaik Imam, Narendiran K
    SRP. 2019; 10(1): s40-s42
    » Abstract » doi: 10.5530/srp.2019.1s.21

  • A Prospective Review on Phyto-Pharmacological Aspects of Andrographis paniculata
    Govindraj Akilandeswari, Arumugam Vijaya Anand, Palanisamy Sampathkumar, Puthamohan Vinayaga Moorthi, Basavaraju Preethi
    SRP. 2019; 10(1): 15-19
    » Abstract » doi: 10.5530/srp.2019.1.3

  • Most Cited Articles