A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?
Abstract
Tara Mandiricha, Maftuchah Rochmanti.
β-adrenergic blockers or β-blockers (BBs) have been the antihypertensive treatment for the past 50 years. Several studies were developed to further explore the therapeutic effects of BB, ranging from use in liver cirrhosis with esophageal varices to involvement in cancer treatment. The Autonomic nervous system (ANS) dysfunction has been shown to cause several of these diseases. Immune suppression, cardiovascular dysfunction, hypertension, and even worse prognosis in cancer patients are due to chronic activation of the sympathetic nervous system (SNS). Based on its mechanism of action, the use of BB drugs has different therapeutic targets, and each has different advantages and side effects. Since the discovery of a new third-generation BB drug that has a complete combination of action, several diseases have hopes of being treated with this agent. Improving survival, hospital discharge, and quality of life affecting patients is the goal of the new therapeutic approach.
How to Cite this Article |
Pubmed Style Mandiricha T, Rochmanti M. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. SRP. 2020; 11(9): 178-186. doi:10.31838/srp.2020.9.30 Web Style Mandiricha T, Rochmanti M. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. http://www.sysrevpharm.org/?mno=4076 [Access: March 29, 2021]. doi:10.31838/srp.2020.9.30 AMA (American Medical Association) Style Mandiricha T, Rochmanti M. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. SRP. 2020; 11(9): 178-186. doi:10.31838/srp.2020.9.30 Vancouver/ICMJE Style Mandiricha T, Rochmanti M. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. SRP. (2020), [cited March 29, 2021]; 11(9): 178-186. doi:10.31838/srp.2020.9.30 Harvard Style Mandiricha, T. & Rochmanti, . M. (2020) A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. SRP, 11 (9), 178-186. doi:10.31838/srp.2020.9.30 Turabian Style Mandiricha, Tara, and Maftuchah Rochmanti. 2020. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. Systematic Reviews in Pharmacy, 11 (9), 178-186. doi:10.31838/srp.2020.9.30 Chicago Style Mandiricha, Tara, and Maftuchah Rochmanti. "A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?." Systematic Reviews in Pharmacy 11 (2020), 178-186. doi:10.31838/srp.2020.9.30 MLA (The Modern Language Association) Style Mandiricha, Tara, and Maftuchah Rochmanti. "A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?." Systematic Reviews in Pharmacy 11.9 (2020), 178-186. Print. doi:10.31838/srp.2020.9.30 APA (American Psychological Association) Style Mandiricha, T. & Rochmanti, . M. (2020) A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. Systematic Reviews in Pharmacy, 11 (9), 178-186. doi:10.31838/srp.2020.9.30 |