A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?

Abstract

Tara Mandiricha, Maftuchah Rochmanti.

β-adrenergic blockers or β-blockers (BBs) have been the antihypertensive treatment for the past 50 years. Several studies were developed to further explore the therapeutic effects of BB, ranging from use in liver cirrhosis with esophageal varices to involvement in cancer treatment. The Autonomic nervous system (ANS) dysfunction has been shown to cause several of these diseases. Immune suppression, cardiovascular dysfunction, hypertension, and even worse prognosis in cancer patients are due to chronic activation of the sympathetic nervous system (SNS). Based on its mechanism of action, the use of BB drugs has different therapeutic targets, and each has different advantages and side effects. Since the discovery of a new third-generation BB drug that has a complete combination of action, several diseases have hopes of being treated with this agent. Improving survival, hospital discharge, and quality of life affecting patients is the goal of the new therapeutic approach.

 

How to Cite this Article
Pubmed Style

Mandiricha T, Rochmanti M. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. SRP. 2020; 11(9): 178-186. 
doi:10.31838/srp.2020.9.30

Web Style

Mandiricha T, Rochmanti M. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. http://www.sysrevpharm.org/?mno=4076 [Access: March 29, 2021]. doi:10.31838/srp.2020.9.30

AMA (American Medical Association) Style

Mandiricha T, Rochmanti M. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. SRP. 2020; 11(9): 178-186. doi:10.31838/srp.2020.9.30



Vancouver/ICMJE Style

Mandiricha T, Rochmanti M. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. SRP. (2020), [cited March 29, 2021]; 11(9): 178-186. doi:10.31838/srp.2020.9.30



Harvard Style

Mandiricha, T. & Rochmanti, . M. (2020) A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. SRP, 11 (9), 178-186. doi:10.31838/srp.2020.9.30



Turabian Style

Mandiricha, Tara, and Maftuchah Rochmanti. 2020. A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. Systematic Reviews in Pharmacy, 11 (9), 178-186. doi:10.31838/srp.2020.9.30



Chicago Style

Mandiricha, Tara, and Maftuchah Rochmanti. "A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?." Systematic Reviews in Pharmacy 11 (2020), 178-186. doi:10.31838/srp.2020.9.30



MLA (The Modern Language Association) Style

Mandiricha, Tara, and Maftuchah Rochmanti. "A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?." Systematic Reviews in Pharmacy 11.9 (2020), 178-186. Print. doi:10.31838/srp.2020.9.30



APA (American Psychological Association) Style

Mandiricha, T. & Rochmanti, . M. (2020) A Novel Pleiotropic Effect of Beta-Blockers: Useful or Not?. Systematic Reviews in Pharmacy, 11 (9), 178-186. doi:10.31838/srp.2020.9.30

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