Abstract

Saade Abdalkareem Jasim, Huda Taher Feisal, Lubna Abdulazeem

Pseudomonas aeruginosa This is study aimed to review previous studies that explain the causes of multiple resistance to these bacteria, and they are also considered Nosocomail bacteria. These bacteria most often infect immunocompromised people, and treatment is often difficult and complicated for those infected due to multiple resistance. This review also demonstrated the benefit of using plant extracts and aromatic oils as alternatives to antibiotics as an inhibitor against P. aeruginosa. During previous studies, it was shown that most of the isolates were distributed among burn infections, wounds, urinary and respiratory tract infections, sputum, and blood poisoning. In addition, this review focused on virulence genes and their major role in bacterial resistance to antibiotics, as well as identifying the main P. aeruginosa genes to be used in the speed of diagnosis. Among the most important of these virulence factors is biofilm formation, β-lactamase production, Pyocyanins, and other enzymes. This review also identified the differences between clinical and environmental isolates and the extent of the effect of random use of antibiotics and the modifications that occurred to bacteria that made them resistant to these antibiotics.