Abstract

Azhar Muhammad Helmi, Akhmad Taufiq Mukti, Agoes Soegianto and Mustofa Helmi Effendi

Sppvibrio. This is a gram-negative battery which causes human and animal vibriosis. In public health, vibriosis is classified as an essential zoonotic disease. In humans, vibriosis is broken down into two groups of cholera and non-cholera infections. Cholerais a gippy tummy complaint that causes substantial mortality and dying in all the world. Vibrio spp noncholera. Occupy moderate to big salinity environments and can be seen in sea water and fish. These germs are the very vital pathogens in humans from theenvironment that come from aquatic and marine habitats. Efforts to control vibriosis in fish farming activities still rely on the use of drugs or antibiotics. Some of the antibiotics commonly used in aquaculture in Indonesia are oxytetracycline, chloramphenicol, erytromycin, streptomycin, neomycin, and enrofloxacin. These types of germicidal are generally used to treat germs illness in fish and shrimp through oral or immersion. However, the use of antibiotics for a certain period of time can cause the fish's body to develop resistance to pathogenic bacteria, polluting the environment and eventually killing the non-target organisms. High antibiotic use can lead to increased germicidal resistance. Awareness raising is critical to limiting inappropriate germicidal use. The goal of this analysis is to reduce the rising and emergence of antibiotic hospitality in V. cholerae, the ecology of germicidal hospitality genes, the antibiotic resistance mechanisms and the genomic parts involved in the spread of antibiotichospitality.