Abstract

Sorabh Sehajpal45551* and Neetu Verma45552

In this review paper we explored the pharmacognostical profile and Anti-hyperglycemic Activity of Gymnema sylvestre. This kind of herbal medications are effective anti-diabetic drugs because they not only enhance glucose and lipid metabolism by increasing insulin release and reducing carbohydrate absorption from the stomach, but they also boost antioxidant levels. Oral anti-hyperglycemic medicines of plant origin (used in traditional medicine) have been the subject of much research. Gymnema sylvestre extract improved the regeneration of the pancreas, liver, and kidney. Gymnema sylvestre has a variety of secondary metabolites, including oleanane, gymnemic acid, gymnemasides (A-F), gymnemic acid (IXVIII) homologue, gymnemic acid A1 and its derivatives, triterpenoidsaponin, alkaloid (Conduritol-A), polypeptide (Gurmarin), and gymnema saponins. This study has provided the groundwork for developing a pharmacognostical profile of medicinal plant growers and collectors. The goal of this review study is to provide a regional profile of the indigenous knowledge system for medicinal plant usage and cultural behaviors related to healing. This study aids in the identification of novel ethnomedicinal plant species in the study region, which may lead to the development of new medicines. The plant toxicity test results indicated that it may be used as an alternative to diabetes therapy with no or little adverse effects. This study confirms the conventional use of indigenous plant-derived natural medicine for treating diabetes mellitus.