Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis
Abstract
Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti
The aim of this study was to find the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of sappan wood ethanol extract (Caesalpinia sappan L.) toward the growth of A. actinomycetemcomitans and P. gingivalis. The randomized post test only control group design was applied to this study. The sappan wood ethanol extract was conducted with maceration method using 96% ethanol. Diluted to 50%, 25%, 12.5%, 6.25%, 3.125%, 1.56%, 0.78%, and 0.39% concentration. The MIC and MBC values of sappan wood ethanol extract toward A. actinomycetemcomitans and P. gingivalis was then known via the evaluation for Colony Forming Units (CFUs) In MH medium. The MIC and MBC of sappan wood ethanol extract toward A. actinomycetemcomitans and P. gingivalis was at 1.56% and 3.125% concentration. The ethanol extract of sappan wood reduces the number of bacterial colonies significantly at p=0.00. This study concluded that the growth of A. actinomycetemcomitans and P. gingivalis can be inhibited by sappan wood ethanol extract (Caesalpinia sappan L.) at MIC 1.56% and MBC 3.125% concentration.
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| Pubmed Style Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. SRP. 2020; 11(3): 349-353. doi:10.5530/srp.2020.3.43 Web Style Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. http://www.sysrevpharm.org/?mno=93389 [Access: March 28, 2021]. doi:10.5530/srp.2020.3.43 AMA (American Medical Association) Style Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. SRP. 2020; 11(3): 349-353. doi:10.5530/srp.2020.3.43 Vancouver/ICMJE Style Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. SRP. (2020), [cited March 28, 2021]; 11(3): 349-353. doi:10.5530/srp.2020.3.43 Harvard Style Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti (2020) Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. SRP, 11 (3), 349-353. doi:10.5530/srp.2020.3.43 Turabian Style Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. 2020. Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. Systematic Reviews in Pharmacy, 11 (3), 349-353. doi:10.5530/srp.2020.3.43 Chicago Style Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. "Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis." Systematic Reviews in Pharmacy 11 (2020), 349-353. doi:10.5530/srp.2020.3.43 MLA (The Modern Language Association) Style Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti. "Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis." Systematic Reviews in Pharmacy 11.3 (2020), 349-353. Print. doi:10.5530/srp.2020.3.43 APA (American Psychological Association) Style Hendrik Setia Budi, Pratiwi Soesilowati, Mitha Jati Wirasti (2020) Antibacterial Activity of Sappan Wood (Caesalpinia sappan L.) against Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis. Systematic Reviews in Pharmacy, 11 (3), 349-353. doi:10.5530/srp.2020.3.43 |
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