Cancer Risk Assessment Based on Family History and Smoking Habits

Abstract

Seyed Matin Malakouti59958*

Cigarette chemicals are harmful to Deoxyribonucleic Acid (DNA). Cells have a strict time repairing DNA damage due to cigarette toxins. Additionally, they break the DNA regions that guard against cancer. Cancer is caused by the accumulation of DNA damage in one cell over time. There are around sixteen cancers which cause risk to human beings due to smoking as follows-cancer of the lung, cancers of the mouth (Squamous cell carcinomas), throat, nose, and sinuses, cancers of the esophagus, cancers of the bladder and ureter (Urothelial carcinoma/transitional cell carcinoma), cancers of kidney (Renal cell carcinoma), cancer of the pancreas (Pancreatic adenocarcinoma), cancer of the stomach (Adenocarcinomas), cancer of the liver (Cholangiocarcinoma), cancer of the cervix and ovary (Ovarian cancers). However, smokers often pass away from other smoking-related conditions, including heart disease, stroke, or emphysema. About 10% to 15% of the smokers acquire lung cancer. People who never smoked or who have quit smoking years ago have also been reported to die from lung cancer. In this research, people suffering from cancer and healthy people were separated using Decision Tree, AdaBoost, and aimed to evaluate a specific gene and smoking history algorithms.

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