Abstract

Baby Prabowo, Ani Melani Maskoen, Arief Budiarto, Fourier, Arif Rachman

The prevalence of periodontal abnormalities is 20-50% of the global population. Periodontitis is inflammatory in 10% -15% of the adult population. Hormones that were affected by microbial infections will reduce the immune system and increase cortisol secretion. Stress triggers the immune response including changes in the oral cavity. Stress-related periodontitis results in increased levels of interleukin-1 beta (IL-1β), interleukin-6 (IL-6), interleukin-10 (IL-10), and the hormone cortisol in the blood, as well as increased plaque formation and gingival inflammation that damages periodontal tissue. In this study, experimental animals were tested with Cone-beam computed tomography (CBCT) for the dominant tracing of the periodontitis region due to psychological stress. Aim: This study aimed to find periodontitis-dominant regions in psychologic stress with CBCT. This study used 6 white Wistar rats with psychological stress (running and moderate exercise fear) and control models. Treatment with 1 day and 5 days and termination with decapitation followed by CBCT test. Psychological stress changes the different mechanisms in the periodontium to activate inflammatory factors that can lead to periodontitis. In this study, to find the dominant periodontitis due to psychological stress by looking at the volume of interest of periodontal tissue widening, the CBCT test showed the area where the distribution width gap and trabecular thickness were measured. This VOI is an area that will determine the distribution width gap and trabeculae thickness. This tracing is to focus on which areas should be of concern in periodontitis therapy. Tracing with CBCT to find the dominant periodontitis region, so that more focus on periodontitis therapy on psychological stress.