Abstract

Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan

Introduction: Dental pulp tissue contains many undifferentiated mesenchymal cells, which have the ability to differentiate into different specialized cells. Induced pluripotent stem cells have been developed by various growth factors. The present study was designed to evaluate the effect of application of a combination BMP2/TGF β1 as capped material for traumatic pulp in osteoporotic rat. Materials and Methods: Twelfth female rats (6 normal rat and other 6 osteoporotic rat)., their maxillary anterior teeth subjected to mechanical traumatized pulptomy, the left tooth has speared without treatment, while the right tooth capped with application of 0.5 μl of BMP2 and 0.5μl of TGF β1 .Evaluation of histological changes includes scoring of pulp inflammation and scoring of morphology and thickness of dentin bridge were estimated for all study groups. Results: Histological examination of tooth with pulptomy capped by BMP-2&TGF β1 for both normal and osteoporotic rat showed formation of reparative dentin bridge and minimal inflammatory response with a significant differences value in comparison to control. Conclusion: The study concludes that application of a combination of BMP-2&TGFβ1 enhanced tooth repair in osteoporotic rat.

How to Cite this Article

Pubmed Style Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan. Effect of Application of BMP2/TGF β1 in Traumatic Pulp of Osteoporotic Rat. SRP. 2020; 11(6): 756-760. doi:10.31838/srp.2020.6.111 Web Style Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan. Effect of Application of BMP2/TGF β1 in Traumatic Pulp of Osteoporotic Rat. http://www.sysrevpharm.org/?mno=118827 [Access: March 29, 2021]. doi:10.31838/srp.2020.6.111 AMA (American Medical Association) Style Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan. Effect of Application of BMP2/TGF β1 in Traumatic Pulp of Osteoporotic Rat. SRP. 2020; 11(6): 756-760. doi:10.31838/srp.2020.6.111 Vancouver/ICMJE Style Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan. Effect of Application of BMP2/TGF β1 in Traumatic Pulp of Osteoporotic Rat. SRP. (2020), [cited March 29, 2021]; 11(6): 756-760. doi:10.31838/srp.2020.6.111 Harvard Style Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan (2020) Effect of Application of BMP2/TGF β1 in Traumatic Pulp of Osteoporotic Rat. SRP, 11 (6), 756-760. doi:10.31838/srp.2020.6.111 Turabian Style Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan. 2020. Effect of Application of BMP2/TGF β1 in Traumatic Pulp of Osteoporotic Rat. Systematic Reviews in Pharmacy, 11 (6), 756-760. doi:10.31838/srp.2020.6.111 Chicago Style Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan. "Effect of Application of BMP2/TGF β1 in Traumatic Pulp of Osteoporotic Rat." Systematic Reviews in Pharmacy 11 (2020), 756-760. doi:10.31838/srp.2020.6.111 MLA (The Modern Language Association) Style Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan. "Effect of Application of BMP2/TGF β1 in Traumatic Pulp of Osteoporotic Rat." Systematic Reviews in Pharmacy 11.6 (2020), 756-760. Print. doi:10.31838/srp.2020.6.111 APA (American Psychological Association) Style Abdulla MW Al-shamma, Athraa Y. Al-Hijazi, Dhuha M Hasan (2020) Effect of Application of BMP2/TGF β1 in Traumatic Pulp of Osteoporotic Rat. Systematic Reviews in Pharmacy, 11 (6), 756-760. doi:10.31838/srp.2020.6.111