Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus)
Abstract
Y Astuti, T Wahyudi, Siswoko
Saturated fats (saturated fatty acids) increase the risk of heart disease due to increased levels of cholesterol, triglycerides, low density lipoprotein (LDL) and decreased high density lipoprotein (HDL). In Indonesia, there are a variety of medicinal plants with suboptimal utilization. Among these plants are breadfruit and to date only been used part of the fruit. It turns out that almost all parts of breadfruit plants have benefits, including the leaves. This part contains flavonoids which are proven to be anti-inflammatory, anti-atherosclerosis and antiplatelet. This study aims to determine the effectiveness of decoction of breadfruit leaves (artocarpus altilis) against decreasing cholesterol levels in the blood of mice. This research is an experimental laboratory study with the design of the posttest only control group design involving a sample of 30 mice and taken using the Federer formula. Pig oil is used to make mice become hypercholesterol through induction. Then, the mice were given boiled water with breadfruit leaves with 3 different doses and measured cholesterol levels in their blood. This study shows that breadfruit leaf decoction has the ability to reduce cholesterol levels with the most significant dose of 0.0571 ml (p = 0.039)
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| Pubmed Style Y Astuti, T Wahyudi, Siswoko. Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus). SRP. 2020; 11(5): 677-679. doi:10.31838/srp.2020.5.95 Web Style Y Astuti, T Wahyudi, Siswoko. Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus). http://www.sysrevpharm.org/?mno=126015 [Access: March 29, 2021]. doi:10.31838/srp.2020.5.95 AMA (American Medical Association) Style Y Astuti, T Wahyudi, Siswoko. Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus). SRP. 2020; 11(5): 677-679. doi:10.31838/srp.2020.5.95 Vancouver/ICMJE Style Y Astuti, T Wahyudi, Siswoko. Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus). SRP. (2020), [cited March 29, 2021]; 11(5): 677-679. doi:10.31838/srp.2020.5.95 Harvard Style Y Astuti, T Wahyudi, Siswoko (2020) Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus). SRP, 11 (5), 677-679. doi:10.31838/srp.2020.5.95 Turabian Style Y Astuti, T Wahyudi, Siswoko. 2020. Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus). Systematic Reviews in Pharmacy, 11 (5), 677-679. doi:10.31838/srp.2020.5.95 Chicago Style Y Astuti, T Wahyudi, Siswoko. "Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus)." Systematic Reviews in Pharmacy 11 (2020), 677-679. doi:10.31838/srp.2020.5.95 MLA (The Modern Language Association) Style Y Astuti, T Wahyudi, Siswoko. "Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus)." Systematic Reviews in Pharmacy 11.5 (2020), 677-679. Print. doi:10.31838/srp.2020.5.95 APA (American Psychological Association) Style Y Astuti, T Wahyudi, Siswoko (2020) Effectiveness of Boiled Water of Breadfruit Leaf (Artocarpus Altilis) on Reducing Cholesterol Levels in The Blood of Mice (Mus Musculus). Systematic Reviews in Pharmacy, 11 (5), 677-679. doi:10.31838/srp.2020.5.95 |
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