Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice
Abstract
Phuc Hung Nguyen, Ngoc Linh Nguyen, Thu Thao Lai, Van Hung Mai.
This study aimed to examine the effects of ethanol-soluble components (Es) in soybean meal (SBM) on plasma lipid level, bile acid concentration, lipase activity and fecal lipid content in mice. The SBM was extracted with aqueous ethanol, then the supernatant was separated from the residue and dried to produce the Es. Four experimental diets were prepared and denoted as CD (standard diet, control), CD+Es10 (CD plus Es 10 g/kg), CD+Es20 (CD plus Es 20 g/kg) and CD+Es30 (CD plus Es 30 g/kg). Nine mice with an initial body weight of 31 g were allocated to each of 8 cages, resulting in two replicate cages per dietary treatment. For 3 weeks, the mice were fed the experimental diets ad libitum. The results showed that the final body weight and weight gain tended to be lower in mice fed diets supplemented with the Es, while feed intake did not differ among the treatment. Mice fed diets supplemented with the Es had lower plasma total cholesterol and triglyceride levels, inferior bile acid concentration and lipase activity in the intestine, but higher lipid content in feces as compared to those fed CD. The findings of the present study suggested that the Es in SBM negatively affected lipid digestion process in Swiss mice and could be used to reduce dyslipidemia and obesity.
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| Pubmed Style Nguyen PH, Nguyen NL, Lai TT, Mai VH. Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice. SRP. 2020; 11(10): 1228-1232. doi:10.31838/srp.2020.10.176 Web Style Nguyen PH, Nguyen NL, Lai TT, Mai VH. Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice. http://www.sysrevpharm.org/?mno=58493 [Access: March 30, 2021]. doi:10.31838/srp.2020.10.176 AMA (American Medical Association) Style Nguyen PH, Nguyen NL, Lai TT, Mai VH. Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice. SRP. 2020; 11(10): 1228-1232. doi:10.31838/srp.2020.10.176 Vancouver/ICMJE Style Nguyen PH, Nguyen NL, Lai TT, Mai VH. Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice. SRP. (2020), [cited March 30, 2021]; 11(10): 1228-1232. doi:10.31838/srp.2020.10.176 Harvard Style Nguyen, P. H., Nguyen, . N. L., Lai, . T. T. & Mai, . V. H. (2020) Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice. SRP, 11 (10), 1228-1232. doi:10.31838/srp.2020.10.176 Turabian Style Nguyen, Phuc Hung, Ngoc Linh Nguyen, Thu Thao Lai, and Van Hung Mai. 2020. Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice. Systematic Reviews in Pharmacy, 11 (10), 1228-1232. doi:10.31838/srp.2020.10.176 Chicago Style Nguyen, Phuc Hung, Ngoc Linh Nguyen, Thu Thao Lai, and Van Hung Mai. "Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice." Systematic Reviews in Pharmacy 11 (2020), 1228-1232. doi:10.31838/srp.2020.10.176 MLA (The Modern Language Association) Style Nguyen, Phuc Hung, Ngoc Linh Nguyen, Thu Thao Lai, and Van Hung Mai. "Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice." Systematic Reviews in Pharmacy 11.10 (2020), 1228-1232. Print. doi:10.31838/srp.2020.10.176 APA (American Psychological Association) Style Nguyen, P. H., Nguyen, . N. L., Lai, . T. T. & Mai, . V. H. (2020) Effects of Ethanol Extract from Soybean Meal on Plasma Lipid Level, Bile acid Concentration, Lipase Activity, Fecal Lipid Content and Weight Gain in Swiss Mice. Systematic Reviews in Pharmacy, 11 (10), 1228-1232. doi:10.31838/srp.2020.10.176 |
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