Abstract

Nabamita Basu, Sainuthana G, Rasmeen Fathima, Lohithalekha Sree, Hephzibha

Fungal infections are pervasive and challenging health issue, impacting millions of individuals globally. With the rise of antifungal resistance and the adverse effects associated with synthetic antifungal agents, there is a growing interest in natural alternatives. This study focuses to study the formulation and development of an antifungal herbal gel, leveraging the therapeutic potential of various medicinal plants. The primary objective is to create topical gel with potent antifungal properties with minimal side effects and enhanced patient compliance. Fruits and leaves of Schinus terebinthifolius (Brazilian pepper tree) were selected for this formulation. The extraction was carried by the maceration and Soxhlet apparatus. The extracts were incorporated into the base gel-prepared formulation prepared in the laboratory. The prepared products were further evaluated for their color, spread ability, pH, washability, consistency and zone of inhibition.