Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?
Abstract
Sumarno Reto Prawiro, Khoirul Anam, Bobi Prabowo, Rendra bramanthi, Avin Ainur Fitrianingsih, Dwi Yuni Nur Hidayati, Siwipeni Imawati, Etty Fitria, and Sri Winarsih
Backgrounds: Covid-19 has become pandemic in the world, including Indonesia. Some Indonesia Covid-19 people tried to consume Honey, Sausseria coctus, and Nigella sativa for curing the Covid-19 disease. From many testimonies, citizen Indonesia people with no need to take hospitalization have reported a cure if they consumed it.
Aims: To make evidence-based medicine that Honey, Sausseria coctus dan Nigella may cure the Covid-19
Methods: We used to post only control design and mice as an animal model. The research divided mice into two groups, and the first group as control received PBS as a placebo. Then the second group, we gave Honey, Sausseria coctus dan Nigella sativa. All of the regiment enters the mouth with special sonde to reach the gastrointestinal organ. After administration regiments a long three weeks, we sacrificed the mice. We evaluated cellular immune responses that are Th2, Th17, and NK cells. We check for humoral immune response, TGF-β, IL-17A, sIgA, IL-4, IL-4, B-def, and IgG.
Results: We got deference Th2 and Th17 between control with treatment group (p=<0.05) statistically from the cellular immune response results. Then there was no statistical difference of NK cells between the control with the treatment group (p=>0.05). For markers, humoral immunity all has deference between control with treatment group (p=>0.05) statistically, but one (IL-17A) have no statistical difference.
Conclusions: We want to continue studying immune responses in humans with COVID-19 if giving Honey, Sausseria coctus, and Nigella sativa.
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| Pubmed Style Prawiro SR, Anam K, Prabowo B, bramanthi R, Fitrianingsih AA, Hidayati DYN, Imawati S, Fitria E, Winarsih aS. Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?. SRP. 2021; 12(1): 1588-1593. doi:10.31838/srp.2021.1.224 Web Style Prawiro SR, Anam K, Prabowo B, bramanthi R, Fitrianingsih AA, Hidayati DYN, Imawati S, Fitria E, Winarsih aS. Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?. http://www.sysrevpharm.org/?mno=56943 [Access: March 29, 2021]. doi:10.31838/srp.2021.1.224 AMA (American Medical Association) Style Prawiro SR, Anam K, Prabowo B, bramanthi R, Fitrianingsih AA, Hidayati DYN, Imawati S, Fitria E, Winarsih aS. Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?. SRP. 2021; 12(1): 1588-1593. doi:10.31838/srp.2021.1.224 Vancouver/ICMJE Style Prawiro SR, Anam K, Prabowo B, bramanthi R, Fitrianingsih AA, Hidayati DYN, Imawati S, Fitria E, Winarsih aS. Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?. SRP. (2021), [cited March 29, 2021]; 12(1): 1588-1593. doi:10.31838/srp.2021.1.224 Harvard Style Prawiro, S. R., Anam, . K., Prabowo, . B., bramanthi, . R., Fitrianingsih, . A. A., Hidayati, . D. Y. N., Imawati, . S., Fitria, . E. & Winarsih, . a. S. (2021) Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?. SRP, 12 (1), 1588-1593. doi:10.31838/srp.2021.1.224 Turabian Style Prawiro, Sumarno Reto, Khoirul Anam, Bobi Prabowo, Rendra bramanthi, Avin Ainur Fitrianingsih, Dwi Yuni Nur Hidayati, Siwipeni Imawati, Etty Fitria, and and Sri Winarsih. 2021. Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?. Systematic Reviews in Pharmacy, 12 (1), 1588-1593. doi:10.31838/srp.2021.1.224 Chicago Style Prawiro, Sumarno Reto, Khoirul Anam, Bobi Prabowo, Rendra bramanthi, Avin Ainur Fitrianingsih, Dwi Yuni Nur Hidayati, Siwipeni Imawati, Etty Fitria, and and Sri Winarsih. "Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?." Systematic Reviews in Pharmacy 12 (2021), 1588-1593. doi:10.31838/srp.2021.1.224 MLA (The Modern Language Association) Style Prawiro, Sumarno Reto, Khoirul Anam, Bobi Prabowo, Rendra bramanthi, Avin Ainur Fitrianingsih, Dwi Yuni Nur Hidayati, Siwipeni Imawati, Etty Fitria, and and Sri Winarsih. "Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?." Systematic Reviews in Pharmacy 12.1 (2021), 1588-1593. Print. doi:10.31838/srp.2021.1.224 APA (American Psychological Association) Style Prawiro, S. R., Anam, . K., Prabowo, . B., bramanthi, . R., Fitrianingsih, . A. A., Hidayati, . D. Y. N., Imawati, . S., Fitria, . E. & Winarsih, . a. S. (2021) Generating the Responses Immune with Honey, Saussurea costus, and Nigella Sativa in Cellular and Humoral May Resolve COVID-19?. Systematic Reviews in Pharmacy, 12 (1), 1588-1593. doi:10.31838/srp.2021.1.224 |
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