Glycemic Control and Peripheral Nerve Function after Healed of Plantar Foot Diabetic Ulcer in Semarang, Indonesia

Abstract

Maria Suryani, Widiastuti Samekto, Heri-Nugroho.

Background: Poor glycemic control and diabetic neuropathy cause the plantar foot diabetic ulcer. Glycemic control improvement has been done to heal the plantar foot diabetic ulcer. Thus, knowing the glycemic control and peripheral nerve function after plantar foot diabetic ulcer is very important. However, the study to evaluate the glycemic control and peripheral nerve function assessment after healed of plantar foot diabetic ulcer has not been conducted yet in Indonesia.
Purpose: The purpose of the study was to evaluate the levels and correlation of glycemic control and peripheral nerve function after healed of plantar foot diabetic ulcer in Semarang, Indonesia.
Methods: A cross-sectional study was conducted in patients with healed plantar foot diabetic ulcers selected consecutively at two hospitals in Semarang Indonesia. Data on glycemic control was measured using HbA1c levels. Peripheral nerve functions were measured using the Diabetic Neuropathy Examination (DNE) scores. Data were analyzed using the Pearson correlation test.
Results: Fifty patients with recently healed plantar foot diabetic ulcer (≤ 12 months) were included in this study. About 42% of the subject had very poor glycemic control (HbA1c>10%) and 92 % had dysfunction of peripheral nerve. There was a significant correlation of glycemic control and function of peripheral nerve after healed plantar foot diabetic ulcer (r = 0.328, p = 0.006).
Conclusion: Most of the patients with healed plantar foot diabetic ulcers had very poor glycemic control and peripheral nerve dysfunction. There was a positive correlation between glycemic control and peripheral nerve functions significantly in patients with healed plantar foot diabetic ulcers. This study recommends that have to make an intensive intervention to improve glycemic control and peripheral nerve function after healed of plantar diabetic foot ulcer.

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