Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients
Abstract
Cut Sheira Elnita, Heru Priyanto, Supriyadi Hari Respati, Uki Retno Budihastuti, Affi Angelia
Objectives: Analyzing IL-6 levels as a predictor of MBCT-Ca effectiveness response and the effect of MBCT-Ca effectiveness in reducing anxiety, depression and improving quality of life (QoL) in cervical cancer patients.
Material and Methods: Randomized controlled trial experimental research with pre and post-test design in the oncology-gynecology clinic with 32 patients from March-August 2019 in Dr. Moewardi hospital, Surakarta. The treatment group, besides the standard therapy, was also given therapy MBCT-Ca 8 times. Levels of IL-6, EORTC-QLQ-C30 scores and HADS scores were assessed for pre and post-treatment.
Results: The average of IL-6 levels in pre-treatment 6.11 ± 6.41, and post-treatment was 7.36 ± 8.74 (p=0.796) while in the control group in the averaged pre-treatment group 8.85 ± 6.48, and post-treatment of 15.61 ± 8.99 (p= 0.063). The control group had increased levels of IL-6 5,525 higher than the increase in IL-6 in the treatment group. In the control group experienced an average increase in HADS scores of 2.00 ± 12.39, the treatment group had a decrease in HADS score of -3.38 ± 9.72 (p=0.043). While the EORTC QLQ C30 score of the control group is increased by an average of 9.25 ± 34.16, the treatment group is decreased by an average EORTC QLQ C30 score of -1.31 ± 19.14 (p=0.167).
Conclusion: There was no significant difference in IL-6 levels in cervical cancer patients who received MBCT-Ca. MBCT-Ca is effective in reducing anxiety and depression, no effect of improving the QoL in cervical cancer patients.
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| Pubmed Style Elnita CS, Priyanto H, Respati SH, Budihastuti UR, Angelia A. Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients. SRP. 2021; 12(1): 563-569. doi:10.31838/srp.2021.1.81 Web Style Elnita CS, Priyanto H, Respati SH, Budihastuti UR, Angelia A. Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients. http://www.sysrevpharm.org/?mno=41038 [Access: March 31, 2021]. doi:10.31838/srp.2021.1.81 AMA (American Medical Association) Style Elnita CS, Priyanto H, Respati SH, Budihastuti UR, Angelia A. Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients. SRP. 2021; 12(1): 563-569. doi:10.31838/srp.2021.1.81 Vancouver/ICMJE Style Elnita CS, Priyanto H, Respati SH, Budihastuti UR, Angelia A. Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients. SRP. (2021), [cited March 31, 2021]; 12(1): 563-569. doi:10.31838/srp.2021.1.81 Harvard Style Elnita, C. S., Priyanto, . H., Respati, . S. H., Budihastuti, . U. R. & Angelia, . A. (2021) Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients. SRP, 12 (1), 563-569. doi:10.31838/srp.2021.1.81 Turabian Style Elnita, Cut Sheira, Heru Priyanto, Supriyadi Hari Respati, Uki Retno Budihastuti, and Affi Angelia. 2021. Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients. Systematic Reviews in Pharmacy, 12 (1), 563-569. doi:10.31838/srp.2021.1.81 Chicago Style Elnita, Cut Sheira, Heru Priyanto, Supriyadi Hari Respati, Uki Retno Budihastuti, and Affi Angelia. "Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients." Systematic Reviews in Pharmacy 12 (2021), 563-569. doi:10.31838/srp.2021.1.81 MLA (The Modern Language Association) Style Elnita, Cut Sheira, Heru Priyanto, Supriyadi Hari Respati, Uki Retno Budihastuti, and Affi Angelia. "Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients." Systematic Reviews in Pharmacy 12.1 (2021), 563-569. Print. doi:10.31838/srp.2021.1.81 APA (American Psychological Association) Style Elnita, C. S., Priyanto, . H., Respati, . S. H., Budihastuti, . U. R. & Angelia, . A. (2021) Interleukin - 6 Relationship on Response of Effectiveness of Mindfulness Based Cognitive Therapy for Cancer in Cervical Cancer Patients. Systematic Reviews in Pharmacy, 12 (1), 563-569. doi:10.31838/srp.2021.1.81 |
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