Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network
Abstract
Van Hung Mai, Xuan Thanh Nguyen, Phuong Lien Lai, Thuy Linh Do, Thi Phuong Le.
Background: Famotidine is one of gastrointestinal drugs which is used by drink or injection, soluble in acids and weakly dissolved in water. It has the effect of reducing gastric secretion by inhibiting histamine at the H2 receptor in the gastric mucosa wall, decreasing the secretion of HCl in gastric juice, the healing of gastric ulcers. Manufacture, In vitro Characterization And In vivo Bioavailability Evaluation of famotidine Loaded 3D-Nano-Cellulose Network (3DNC) by bacteria and Used for Oral Administration.
Methods: Famotidine is a gastrointestinal H2-receptor antagonist drug with low bioavailability (40-45%). 3DNC can be produced from bacteria living in fermented green tea and is the material containing nano-sized fibers which is capable of loading Famotidine to form a prolonged release therapy to improve drug bioavailability.
Results: This research has been produced 3DNC materials from bacteria in some nutrient media; it has used scanning electron microscope (SEM) to determine the 3DNC structure, spectrophotometer FT-IR to determine drug interaction to 3DNC, high performance liquid chromatography (HPLC) to determine Famotidine in rabbit plasma.
Conclusion: Three-dimensional nano-cellulose network has an involvement of the nano-sized cellulose fibers with three dimensional networks that are capable of loading Famotidine drug.
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| Pubmed Style Mai VH, Nguyen XT, Lai PL, Do TL, Le TP. Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network. SRP. 2020; 11(7): 309-313. doi:10.31838/srp.2020.7.48 Web Style Mai VH, Nguyen XT, Lai PL, Do TL, Le TP. Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network. http://www.sysrevpharm.org/?mno=127504 [Access: March 29, 2021]. doi:10.31838/srp.2020.7.48 AMA (American Medical Association) Style Mai VH, Nguyen XT, Lai PL, Do TL, Le TP. Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network. SRP. 2020; 11(7): 309-313. doi:10.31838/srp.2020.7.48 Vancouver/ICMJE Style Mai VH, Nguyen XT, Lai PL, Do TL, Le TP. Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network. SRP. (2020), [cited March 29, 2021]; 11(7): 309-313. doi:10.31838/srp.2020.7.48 Harvard Style Mai, V. H., Nguyen, . X. T., Lai, . P. L., Do, . T. L. & Le, . T. P. (2020) Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network. SRP, 11 (7), 309-313. doi:10.31838/srp.2020.7.48 Turabian Style Mai, Van Hung, Xuan Thanh Nguyen, Phuong Lien Lai, Thuy Linh Do, and Thi Phuong Le. 2020. Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network. Systematic Reviews in Pharmacy, 11 (7), 309-313. doi:10.31838/srp.2020.7.48 Chicago Style Mai, Van Hung, Xuan Thanh Nguyen, Phuong Lien Lai, Thuy Linh Do, and Thi Phuong Le. "Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network." Systematic Reviews in Pharmacy 11 (2020), 309-313. doi:10.31838/srp.2020.7.48 MLA (The Modern Language Association) Style Mai, Van Hung, Xuan Thanh Nguyen, Phuong Lien Lai, Thuy Linh Do, and Thi Phuong Le. "Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network." Systematic Reviews in Pharmacy 11.7 (2020), 309-313. Print. doi:10.31838/srp.2020.7.48 APA (American Psychological Association) Style Mai, V. H., Nguyen, . X. T., Lai, . P. L., Do, . T. L. & Le, . T. P. (2020) Manufacture and Assessment of the absorption capability of famotidine to 3D-nano-cellulose network. Systematic Reviews in Pharmacy, 11 (7), 309-313. doi:10.31838/srp.2020.7.48 |
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