Methods of Preparation and Characterization of Orodispersible Film: A Review

Abstract

Fitha TV58455*, K Selvaraju58456 and NL Gowrisankar58457

One of the latest dosage forms, Orodispersible Film (ODF), can be easily dissolved in the mouth without the need for water. One of the key components used to make Orodispersible Film is polymer. While making ODF, both organic and synthetic polymers are utilised. Additionally, other approaches are discussed for developing ODF. The focus of this review involves information regarding Orodispersible Film preparation and usage of natural and synthetic polymers as film formers for quick film disintegration in the buccal cavity. Additionally, it is regarded as an easy-to-take dose form since the saliva in the mouth causes the film to disintegrate quickly. Drug permeability can be increased by incorporating the permeation enhancer, which also increases bioavailability. One can also administer Orodispersible Film dosage form for directly treating the oral diseases. When compared to buccal gel and buccal tablets, ODF is more practical for daily consumption. ODF helps with patient compliance to some extent. The idea of Orodispersible Films is mostly beneficial for specific population like geriatrics and children. The most frequently utilised method for preparing ODF is solvent casting process in both the industrial and laboratory settings.

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