Abstract

Emy Koestanti Sabdoningrum, Sri Hidanah, Sri Chusniati, Moh. Sukmanadi, Sri Agus Sudjarwo, Sarmanu

Introduction: Escherichia coliinfection cause death and declining production of broiler farm in Indonesia frequently. Its infection occurs systemic and lead to bacteremia.Objective: The aim of this study was to reveal nano-herb of meniran (Phyllanthus niruri) extract capability as antibacterial against Escherichia coli. Methods: Obtained data was tested parametrically using prohibit analyzes. The method for the research was dilution method. Before the substance was diluted, phytochemical screening on the substance was conducted. Results:The result of the screening revealed that meniran extract contains some compounds such as alkaloid, tannin, flavonoid, saponin, and steroid. The result of MIC assay was not capable to be observed due to blackish colour of the extract which covered the medium. MBC assay showed that nano-herb of meniran extract 5% of doze was capable to against growth of Escherichia coli.Conclusion:In conclusion, meniran nano-herb has capability as antibacterial against APEC.