Optimal Opioid Analgesia in Early Postoperative Period with and without Addition of NSAIDS in Cardiac Surgery

Abstract

Edīte Voliņeca69331*, Elīna Skaida69332 and Baiba Arkliņa69333

Opioid analgesia is used as a standard postoperative analgesia in cardiac surgery patients. Opioids hold several unwanted side effects as nausea, vomiting, constipation, physical dependence, and even respiratory depression. Multimodal therapy is proposed as the best option for decreasing postoperative pain while reducing side effects. NSAIDs are among the commonly used agents. In this study we evaluate the dosages of fentanyl for appropriate analgesia management and lower side effects, additionally looking at the possibility of a threshold at which NSAID agents could be added to opioid analgesia therapy and is of high importance to effective pain reduction and decrease the addition of unnecessary medication.