Plant Flavonoids as Potential Source of Future Antimalarial leads
Abstract
Mithun Rudrapal* and Dipak Chetia
In this article, a comprehensive review on bioactive flavonoids that are abundant in medicinal and functional food (dietary) plants has been made, with special reference to antimalarial flavonoid molecules. Flavonoids have been found to exist in plants/plant medicines comprising numerous poly-phenolic compounds with a wide structural diversity having pharmacologi-cal potential in diverse range of therapeutic areas. Flavonoids derived from certain dietary plants described herein have been investigated for their an-timalarial effectiveness against malaria parasites, particularly Plasmodium falciparum. The biological target specificity of their antimalarial action is so interesting that they act at protein targets at molecular level other than the conventional antimalarial targets. This approach may be a basis of estab-lishing plant flavonoids as future antimalarial leads for the development of new and potent antimalarial drug molecules.
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Pubmed Style Mithun Rudrapal and Dipak Chetia. Plant Flavonoids as Potential Source of Future Antimalarial leads. SRP. 2017; 8(1): 13-18. doi:10.5530/srp.2017.1.4 Web Style Mithun Rudrapal and Dipak Chetia. Plant Flavonoids as Potential Source of Future Antimalarial leads. http://www.sysrevpharm.org/?mno=302644558 [Access: March 28, 2021]. doi:10.5530/srp.2017.1.4 AMA (American Medical Association) Style Mithun Rudrapal and Dipak Chetia. Plant Flavonoids as Potential Source of Future Antimalarial leads. SRP. 2017; 8(1): 13-18. doi:10.5530/srp.2017.1.4 Vancouver/ICMJE Style Mithun Rudrapal and Dipak Chetia. Plant Flavonoids as Potential Source of Future Antimalarial leads. SRP. (2017), [cited March 28, 2021]; 8(1): 13-18. doi:10.5530/srp.2017.1.4 Harvard Style Mithun Rudrapal and Dipak Chetia (2017) Plant Flavonoids as Potential Source of Future Antimalarial leads. SRP, 8 (1), 13-18. doi:10.5530/srp.2017.1.4 Turabian Style Mithun Rudrapal and Dipak Chetia. 2017. Plant Flavonoids as Potential Source of Future Antimalarial leads. Systematic Reviews in Pharmacy, 8 (1), 13-18. doi:10.5530/srp.2017.1.4 Chicago Style Mithun Rudrapal and Dipak Chetia. "Plant Flavonoids as Potential Source of Future Antimalarial leads." Systematic Reviews in Pharmacy 8 (2017), 13-18. doi:10.5530/srp.2017.1.4 MLA (The Modern Language Association) Style Mithun Rudrapal and Dipak Chetia. "Plant Flavonoids as Potential Source of Future Antimalarial leads." Systematic Reviews in Pharmacy 8.1 (2017), 13-18. Print. doi:10.5530/srp.2017.1.4 APA (American Psychological Association) Style Mithun Rudrapal and Dipak Chetia (2017) Plant Flavonoids as Potential Source of Future Antimalarial leads. Systematic Reviews in Pharmacy, 8 (1), 13-18. doi:10.5530/srp.2017.1.4< |