Abstract

Preethi S, Vikas Jain, Amit B Patil, Siree K G, Sowmya B.A

In pursuit of new medicinal compounds in traditional medicinal plants growing in America (south, north, central part), Bursera Simaruba is one such potential medicinal tree. Phytochemical analysis of methanolic extraction of the bark and leaf hexane extract of the plant has triggered the isolation of quite a few phytoconstituents. The whole plant of B. Simaruba is rich in resins, lignans, terpenes, steroids etc. The various parts of the plant are renowned for their inhibitory action towards many bacteria, virus, fungi and protozoa. It also shows antioxidant activity and is proven to cause programmed cell death (apoptosis). It also shows action against inflammation. It is mainly being researched for its anti-cancer activity. Finally, the plant is known in folk medicine for its use as anti-snake venom treatment. Regulatory aspects of use and formulation of herbal medicines and alternative medicines around the world and their legal status respect to their countries is an important aspect. The present review includes possibilities and insights through potential studies into herbal formulation as well as the regulatory aspects for herbal medicines around world.