Abstract

Bharat Jadhav72462*, Rutja Daas72457 and Sahil T Sheikh72458

The evaluation of diclofenac potassium tablets involved rigorous testing to ensure quality and efficacy. Tests included hardness assessment to gauge tablet strength, friability testing to determine resistance to action analysis was conducted to ensure uniformity among tablets. This comprehensive Ethylene-Vinyl Acetate (EVA) abrasion and disintegration tests to assess dissolution properties. Additionally, weight evaluation provides valuable insights into the tablets physical characteristics, aiding in the assurance of product quality and consistency. This study focuses on the comprehensive evaluation of diclofenac potassium tablets, an important step in ensuring their quality and performance. Hardness testing was employed to measure the tablets resistance to breakage, indicating their strength and durability. Friability assessment gauged the tablets susceptibility to abrasion, providing insights into their structural integrity during handling and transport. Disintegration tests were conducted to examine the tablets dissolution properties, important for predicting their efficacy upon ingestion. Weight variation analysis ensured uniformity in tablet mass, a critical factor in dosage accuracy and overall product consistency. The findings from these tests collectively contribute to a thorough understanding of the physical attributes of diclofenac potassium tablets. This information is essential for quality control, helping to guarantee that each tablet meets the required standards for hardness, friability, disintegration, and weight variation. As a result, this evaluation provides valuable data for pharmaceutical manufacturers, regulatory authorities, and healthcare professionals, reinforcing the reliability and effectiveness of diclofenac potassium tablets in therapeutic applications.