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Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries

Abstract

Fajriani1, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari.

Early Childhood caries (ECC) define as the most common dental health problem in children. ECC is severe tooth decay and develops quickly and causes long-standing dental problems among children. The objective of this study was to make toothpaste from green tea polyphenol for use among children with ECC. Next will be a beta growth factor transforming examination (TGF-β1) to review tertiary dentin formation in children's teeth after using green tea catechin toothpaste so that it can be used as a topical treatment without any restoration. This study was an experimental study with a pre and post design, which was started by making green tea toothpaste catechins accompanied by an optimal inhibitory test for Streptococcus mutated bacteria. Further studies of patients with ECC were given Green Tea Polyphenol toothpaste and TGFβ-1 and BMP-2 measurements were taken before and after the experiment. The results showed an increase in TGFβ-1 and BMP-2 levels after using green tea catechin toothpaste in the first 5 minutes increased but decreased in 10 minutes. TGFβ-1 test results produced P <0.05 (0.036) significant in the first 5 minutes after the use of green tea catechin toothpaste, BMP-2 P> 0.05 (0.705), 5 minutes or 10 minutes after the results of the first treatment test 2 TGFβ -1 produces P> 0.05 (0.086) and BMP-2 P> 0.05 (0.600). Based on the research, it was concluded that topical therapy was found to be more effective and safer natural ingredients to stop progressive caries and form a tertiary, especially among ECC’s children.

How to Cite this Article
Pubmed Style

Fajriani, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari. Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries. SRP. 2020; 11(12): 42-47. doi:10.31838/srp.2020.12.7

Web Style

Fajriani, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari. Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries. http://www.sysrevpharm.org/?mno=127111 [Access: March 29, 2021]. doi:10.31838/srp.2020.12.7

AMA (American Medical Association) Style

Fajriani, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari. Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries. SRP. 2020; 11(12): 42-47. doi:10.31838/srp.2020.12.7


Vancouver/ICMJE Style

Fajriani, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari. Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries. SRP. (2020), [cited March 29, 2021]; 11(12): 42-47. doi:10.31838/srp.2020.12.7


Harvard Style

Fajriani, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari (2020) Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries. SRP, 11 (12), 42-47. doi:10.31838/srp.2020.12.7


Turabian Style

Fajriani, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari. 2020. Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries. Systematic Reviews in Pharmacy, 11 (12), 42-47. doi:10.31838/srp.2020.12.7


Chicago Style

Fajriani, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari. "Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries." Systematic Reviews in Pharmacy 11 (2020), 42-47. doi:10.31838/srp.2020.12.7


MLA (The Modern Language Association) Style

Fajriani, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari. "Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries." Systematic Reviews in Pharmacy 11.12 (2020), 42-47. Print. doi:10.31838/srp.2020.12.7


APA (American Psychological Association) Style

Fajriani, Sartini, Sherly Horax, Adam Malik, Asmawati, Atika Balqis, Dwi Putri Wulansari (2020) Role of Green Tea Catechins Toothpaste on Transforming Growth Factor-β1 (TGF-β1) and Bone Morphogenetic-2 (BMP-2) on Early Childhood Caries. Systematic Reviews in Pharmacy, 11 (12), 42-47. doi:10.31838/srp.2020.12.7

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