Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride

Abstract

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium

The complexes of Co (II), Ni (II), Cu (II), Zn (II), Cd (II), Pt (II), and Au (III) were prepared from the complexation reaction between the new Schiff base ligand and metal ions. This ligand(3,4-bis(((E)-1-(2-(((E)-(3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl) methylene) amino) phenyl) ethylidene) amino) phenyl) phenyl) methanone was derived from the condensation reaction of 3,4-diamino benzophenone, 2-amino acetophenone, and pyridoxal hydrochloride. The ligand and its complexes were characterized by C.H.N elemental analysis, Uv-Vis, FT-IR, 1H-NMR and molar conductivity, Atomic absorption, magnetic moment measurements and mass spectra studies. The results of this studies show the coordination sites for the ligand with the metal ion were to be through oxygen of the hydroxyl group, and the nitrogen of azomethine groups. The electronic spectral and magnetic measurement data predict octahedral structure of the complexes, except for Pt (II) and Au (III) complexes were suggested a square planar geometry. All complexes show that nonelectrolytes properties, but Pt (II) and Au (III) complexes are electrolyte nature. New Schiff base ligand and its metal complexes were Screened against bacterial and fungal strains and their preliminary results compounds exhibited the high effect of activity. This may be attributed to the impact of both the chelate effect of new Schiff bases ligand and the role of the metal in these complexes.

 

How to Cite this Article
Pubmed Style

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium. Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride. SRP. 2021; 12(1): 371-383. 
doi:10.31838/srp.2021.1.58

Web Style

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium. Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride. http://www.sysrevpharm.org/?mno=36124 [Access: March 28, 2021]. doi:10.31838/srp.2021.1.58

AMA (American Medical Association) Style

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium. Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride. SRP. 2021; 12(1): 371-383. doi:10.31838/srp.2021.1.58



Vancouver/ICMJE Style

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium. Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride. SRP. (2021), [cited March 28, 2021]; 12(1): 371-383. doi:10.31838/srp.2021.1.58



Harvard Style

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium (2021) Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride. SRP, 12 (1), 371-383. doi:10.31838/srp.2021.1.58



Turabian Style

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium. 2021. Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride. Systematic Reviews in Pharmacy, 12 (1), 371-383. doi:10.31838/srp.2021.1.58



Chicago Style

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium. "Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride." Systematic Reviews in Pharmacy 12 (2021), 371-383. doi:10.31838/srp.2021.1.58



MLA (The Modern Language Association) Style

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium. "Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride." Systematic Reviews in Pharmacy 12.1 (2021), 371-383. Print. doi:10.31838/srp.2021.1.58



APA (American Psychological Association) Style

Muna Abass Hadi, Mithaq Saeed Mohammed, Afaq Jaber Kadhium (2021) Synthesis, Characterization and Spectral Studies and Biological Screening Study of Transition Metal Complexes with New Heterocyclic Ligand Derived from Pyridoxal Hydrochloride. Systematic Reviews in Pharmacy, 12 (1), 371-383. doi:10.31838/srp.2021.1.58

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