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The Effect of 5-Hydroxy-3'-Methoxy-7, 4'-Diacetyl on Aortic Smooth Muscle under Hypoxic Conditions

Abstract

Mirzayeva Yulduzkhon Takhirzhonovna27355, Omonturdiev Sirojiddin Zoirovich27357*, Zaripov Abdisalim Abdikarimovich27358, Usmanov Pulat Bekmuratovich27359, Esimbetov Adilbay Tlepovich27360 and Eshbakova Komila Alibekovna27361

The aim of this study was to examine the effect of flavone-5-hydroxy-3'-a metaoxy-7,4'-diacetyl derivative of the flavonoid chrysoeriol isolated from the Inula capsicum plant on the contractile activity of rat aor ta preparations under hypoxic conditions in vitro  and modern ideas about the molecular mechanisms of hypoxia development, its maintenance and the possibilities of pharmacological correction.

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