The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine
Abstract
Suwoyo, Lumastari Ajeng Wijayanti, Dwi Estuning Rahayu.
Measles is an infectious disease that attacks children. The incidence of measles in Indonesia is still quite high. The results of the immunization implementation report stated that the achievement of immunization targets for children under five reached more than 90%. However, not all children in Indonesia can enjoy the benefits of the immunization that has been given. Humans in their lives cannot avoid benzo [a] pyrene compounds, either directly or indirectly. The effect of benzo [a] pyrene on changes in immune cell profile in mice (Mus musculus L) was analyzed in vivo by giving intra-muscular injection of benzo [a] pyrene 20 mg / kg BW 2 times / week for 4 weeks. Immune cell profiles were analyzed using flowcytometry. The analysis was continued with statistical analysis using SPSS software using the one way ANOVA test with a significance level (p-value <0.05). The immune cell profile after week 4 in the group of mice that had received the vaccine and given exposure to benzo [a] pyrene was repression occurred in CD11b + IL1 +, CD11b + IL17 + activation occurred, while CD4 + CD25 + cell profiles experienced a downregulation reaction.
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| Pubmed Style , Wijayanti LA, Rahayu DE. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. SRP. 2020; 11(9): 926-930. doi:10.31838/srp.2020.9.135 Web Style , Wijayanti LA, Rahayu DE. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. http://www.sysrevpharm.org/?mno=23317 [Access: March 30, 2021]. doi:10.31838/srp.2020.9.135 AMA (American Medical Association) Style , Wijayanti LA, Rahayu DE. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. SRP. 2020; 11(9): 926-930. doi:10.31838/srp.2020.9.135 Vancouver/ICMJE Style , Wijayanti LA, Rahayu DE. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. SRP. (2020), [cited March 30, 2021]; 11(9): 926-930. doi:10.31838/srp.2020.9.135 Harvard Style , Wijayanti, . L. A. & Rahayu, . D. E. (2020) The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. SRP, 11 (9), 926-930. doi:10.31838/srp.2020.9.135 Turabian Style , Lumastari Ajeng Wijayanti, and Dwi Estuning Rahayu. 2020. The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. Systematic Reviews in Pharmacy, 11 (9), 926-930. doi:10.31838/srp.2020.9.135 Chicago Style , Lumastari Ajeng Wijayanti, and Dwi Estuning Rahayu. "The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine." Systematic Reviews in Pharmacy 11 (2020), 926-930. doi:10.31838/srp.2020.9.135 MLA (The Modern Language Association) Style , Lumastari Ajeng Wijayanti, and Dwi Estuning Rahayu. "The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine." Systematic Reviews in Pharmacy 11.9 (2020), 926-930. Print. doi:10.31838/srp.2020.9.135 APA (American Psychological Association) Style , Wijayanti, . L. A. & Rahayu, . D. E. (2020) The Effect of Benzo [A] Pyrene on Changes in the Profile of CD11B + IL1 +, CD11B + IL17 +, CD4 + CD25 + in Mice (MUS MUSCULUS, L) after Getting Paramicsovirus Vaccine. Systematic Reviews in Pharmacy, 11 (9), 926-930. doi:10.31838/srp.2020.9.135 |
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