Abstract

Muhammad Ardi Munir, Hendra Kuganda, Amirah Basry.

Corona Virus Disease 2019 (COVID-9) is an acute respiratory infection caused by extreme acute coronavirus-2 (SARS-CoV-2) respiratory syndrome. WHO has designated COVID-19 as a pandemic with a very high mortality rate and increasing very rapidly, in only 3 months COVID- 19 has infected 1.133046 people and in many cases only 14 days COVID-19 has caused death? With very high mortality and mordibility rates, no effective and safe of antivirus treatment has yet been found to cure COVID-19, so research is needed to find the most effective and safe of antivirus drugs to cure COVID-19. To know the best and safe of antivirus medication to cure COVID-19. This research uses a structured analysis focused on preferred reporting items for systematic reviews and meta-analyzes (PRISMA) in order to classify all existing literature with appropriate keywords. The database using PRISMA (Preferred Reporting Items for Systematic Reviews & Meta Analyses) for instruments and used flowcharts based on the 2009 PRISMA checklist and based on inclusion and exclusion criteria, we found 6 anti-virus drugs used to treat SARS-CoV-1 or MERS-CoV and very potential to treat COVID-19, that is Favipiravir (Avigan, Favilavir), Lopinavir and Ritonavir (LPV / RTV; Kaletra) , Neuraminidase inhibitors (eg, oseltamivir), Umifenovir (Arbidol) Remdesivir, and Baloxavir. The most efficacy and safe of anti-virus is Favipiravir because this drug can improve significantly time-to-relief for fever and cough and is associated with manageable adverse effects.

How to Cite this Article

Pubmed Style Munir MA, Kuganda H, Basry A. The Efficacy and Safety of Antivirus Drugs for COVID-19: A Systematic Review. SRP. 2020; 11(7): 162-166. doi:10.31838/srp.2020.7.26 Web Style Munir MA, Kuganda H, Basry A. The Efficacy and Safety of Antivirus Drugs for COVID-19: A Systematic Review. http://www.sysrevpharm.org/?mno=125669 [Access: March 29, 2021]. doi:10.31838/srp.2020.7.26 AMA (American Medical Association) Style Munir MA, Kuganda H, Basry A. The Efficacy and Safety of Antivirus Drugs for COVID-19: A Systematic Review. SRP. 2020; 11(7): 162-166. doi:10.31838/srp.2020.7.26 Vancouver/ICMJE Style Munir MA, Kuganda H, Basry A. The Efficacy and Safety of Antivirus Drugs for COVID-19: A Systematic Review. SRP. (2020), [cited March 29, 2021]; 11(7): 162-166. doi:10.31838/srp.2020.7.26 Harvard Style Munir, M. A., Kuganda, . H. & Basry, . A. (2020) The Efficacy and Safety of Antivirus Drugs for COVID-19: A Systematic Review. SRP, 11 (7), 162-166. doi:10.31838/srp.2020.7.26 Turabian Style Munir, Muhammad Ardi, Hendra Kuganda, and Amirah Basry. 2020. The Efficacy and Safety of Antivirus Drugs for COVID-19: A Systematic Review. Systematic Reviews in Pharmacy, 11 (7), 162-166. doi:10.31838/srp.2020.7.26 Chicago Style Munir, Muhammad Ardi, Hendra Kuganda, and Amirah Basry. "The Efficacy and Safety of Antivirus Drugs for COVID-19: A Systematic Review." Systematic Reviews in Pharmacy 11 (2020), 162-166. doi:10.31838/srp.2020.7.26 MLA (The Modern Language Association) Style Munir, Muhammad Ardi, Hendra Kuganda, and Amirah Basry. "The Efficacy and Safety of Antivirus Drugs for COVID-19: A Systematic Review." Systematic Reviews in Pharmacy 11.7 (2020), 162-166. Print. doi:10.31838/srp.2020.7.26 APA (American Psychological Association) Style Munir, M. A., Kuganda, . H. & Basry, . A. (2020) The Efficacy and Safety of Antivirus Drugs for COVID-19: A Systematic Review. Systematic Reviews in Pharmacy, 11 (7), 162-166. doi:10.31838/srp.2020.7.26