The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq
Abstract
Hayam Khalis Al-Masoudi, Asmaa Khadhm, Faliha Habeb AL-Karaawy.
Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite causing toxoplasmosis in animals and humans. It causes serious problems to the pregnant women that lead to incidence an abortion. Essential vitamins and minerals (for examplevitamin D and zinc metale) are support maternal health and fetal development throughout gestation through processes that are integrated across maternal, placental and fetal compartments. This study was aimed to investigate the alterations in the levels of vitamins D ,element Zn and MDA in the sera of women with toxoplasmosis with a history of recurrent miscarriage , and compare them with the results of age matched healthy volunteers as control group. Sixty patients with positive anti-T gondii (IgG) antibodies and 28 healthy individuals were included in this study. The levels of serum Zn was measured by Atomic absorption spectrophotometry Systems, while serum vitamin D and MDA concentrations were measured by using enzyme-linked immunoassay (ELISA) technique. The level of serum zinc significantly decrease in women with age (34-43years ) it was (37.73 µg/dl ( in compare with control group , while level of Vitamin D was significantly decrease in women with age (24-33years ) it was (146.3ng/mL). The present study also confirms that level of Malondialdehyde (MDA) in miscarriage women was slighty increase (183.249 ± 83.169ng/mL) in compare with control group (162.678±65.589 ng/mL) respectively in age group 24-33years. In conclusion, the results indicated that the levels of antioxidant vitamins, zinc and MDA may have an important role to increase possibility of exposure to toxoplasmosis in women.
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Pubmed Style Al-Masoudi HK, AK, AL-Karaawy FH. The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq. SRP. 2020; 11(7): 443-449. doi:10.31838/srp.2020.7.64 Web Style Al-Masoudi HK, AK, AL-Karaawy FH. The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq. http://www.sysrevpharm.org/?mno=128794 [Access: March 30, 2021]. doi:10.31838/srp.2020.7.64 AMA (American Medical Association) Style Al-Masoudi HK, AK, AL-Karaawy FH. The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq. SRP. 2020; 11(7): 443-449. doi:10.31838/srp.2020.7.64 Vancouver/ICMJE Style Al-Masoudi HK, AK, AL-Karaawy FH. The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq. SRP. (2020), [cited March 30, 2021]; 11(7): 443-449. doi:10.31838/srp.2020.7.64 Harvard Style Al-Masoudi, H. K., , . A. K. & AL-Karaawy, . F. H. (2020) The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq. SRP, 11 (7), 443-449. doi:10.31838/srp.2020.7.64 Turabian Style Al-Masoudi, Hayam Khalis, Asmaa Khadhm, and Faliha Habeb AL-Karaawy. 2020. The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq. Systematic Reviews in Pharmacy, 11 (7), 443-449. doi:10.31838/srp.2020.7.64 Chicago Style Al-Masoudi, Hayam Khalis, Asmaa Khadhm, and Faliha Habeb AL-Karaawy. "The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq." Systematic Reviews in Pharmacy 11 (2020), 443-449. doi:10.31838/srp.2020.7.64 MLA (The Modern Language Association) Style Al-Masoudi, Hayam Khalis, Asmaa Khadhm, and Faliha Habeb AL-Karaawy. "The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq." Systematic Reviews in Pharmacy 11.7 (2020), 443-449. Print. doi:10.31838/srp.2020.7.64 APA (American Psychological Association) Style Al-Masoudi, H. K., , . A. K. & AL-Karaawy, . F. H. (2020) The Impact of Toxoplasma gondii Infection on The Serum Zinc, Vitamin D and Malondialdehyde Levels among Recurrent Miscarriage Women in Babylon Province-Iraq. Systematic Reviews in Pharmacy, 11 (7), 443-449. doi:10.31838/srp.2020.7.64 |