Abstract

Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty

This systematic review tries to determine the use of the various types of marine biota in bone tissue regeneration. There were 637 articles gathered from PubMed, Wiley, and google scholar databases. Title selection obtained 172 reports and 69 duplications. Abstract selection resulted in 34 articles. The full-text selection was done afterward and produced 11 articles, which were finally analyzed by the authors. The research was done by 11 groups of researchers who came from 10 different countries. The countries were Spain, Tunisia, India, Brazil, Poland, Singapore, England, China, Malaysia, and South Africa. Marine biota that were used in the studies were shark teeth, pearl, fish skin, seaweed, sponge, cockle shell, and deep-sea fish head. The activated marker that appeared in the bone formation process by the stimulation of the material was alkaline phosphatase, collagen 1-a-1, osteopontin, osteocalcin, and runx2. Various types of marine biota dan are used in bone tissue regeneration through osteoblastic stimulation with the activity of bone formation markers, such as Alkaline phosphatase, collagen 1-a-1, osteocalcin, runx2, as well as other markers.

 

How to Cite this Article

Pubmed Style Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty. The Use of Marine Biota in Bone Tissue Regeneration: A Systematic Review. SRP. 2020; 11(12): 31-34. doi:10.31838/srp.2020.12.5 Web Style Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty. The Use of Marine Biota in Bone Tissue Regeneration: A Systematic Review. http://www.sysrevpharm.org/?mno=127104 [Access: March 29, 2021]. doi:10.31838/srp.2020.12.5 AMA (American Medical Association) Style Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty. The Use of Marine Biota in Bone Tissue Regeneration: A Systematic Review. SRP. 2020; 11(12): 31-34. doi:10.31838/srp.2020.12.5 Vancouver/ICMJE Style Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty. The Use of Marine Biota in Bone Tissue Regeneration: A Systematic Review. SRP. (2020), [cited March 29, 2021]; 11(12): 31-34. doi:10.31838/srp.2020.12.5 Harvard Style Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty (2020) The Use of Marine Biota in Bone Tissue Regeneration: A Systematic Review. SRP, 11 (12), 31-34. doi:10.31838/srp.2020.12.5 Turabian Style Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty. 2020. The Use of Marine Biota in Bone Tissue Regeneration: A Systematic Review. Systematic Reviews in Pharmacy, 11 (12), 31-34. doi:10.31838/srp.2020.12.5 Chicago Style Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty. "The Use of Marine Biota in Bone Tissue Regeneration: A Systematic Review." Systematic Reviews in Pharmacy 11 (2020), 31-34. doi:10.31838/srp.2020.12.5 MLA (The Modern Language Association) Style Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty. "The Use of Marine Biota in Bone Tissue Regeneration: A Systematic Review." Systematic Reviews in Pharmacy 11.12 (2020), 31-34. Print. doi:10.31838/srp.2020.12.5 APA (American Psychological Association) Style Edy Machmud, Muhammad Ikbal, Irfan Dammar, Darmiaty (2020) The Use of Marine Biota in Bone Tissue Regeneration: A Systematic Review. Systematic Reviews in Pharmacy, 11 (12), 31-34. doi:10.31838/srp.2020.12.5