The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen
Abstract
Yusnidar Yusuf
Laccases are multi-copper oxidases that can act as a catalyst the one-electron oxidation of aromatic and non-aromatic compounds which include substituted phenols, several inorganic ions, and various non-phenolic compounds with the concomitant reduction of O2 to H2O. This research aims to utilize laccase-functionalized graphene oxide (GO) as effective biodegradation of pharmaceutical industry waste: diclofenac and ibuprofen. In this study, Laccase enzyme was isolated from white oyster mushroom and immobilized with GO that was synthesized from graphite powder. Afterward, GO-laccase would be applied in degradation of diclofenac and ibuprofen. The experimental results indicated the GO-laccase had a good biodegradability to degrade pharmaceutical industry waste. Some of the compounds derived from diclofenac are N-(2,6-Dichlorophenyl) indolin-2-one, 2-(2,6-Dichloro-phenylamino)-benzaldehyde, and 2,6-Dichloroaniline, and ibuprofen is 4-Isobutylacetophenone.
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| Pubmed Style Yusnidar Yusuf. The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen. SRP. 2020; 11(1): 536-544. doi:10.5530/srp.2020.1.67 Web Style Yusnidar Yusuf. The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen. http://www.sysrevpharm.org/?mno=85742 [Access: March 29, 2021]. doi:10.5530/srp.2020.1.67 AMA (American Medical Association) Style Yusnidar Yusuf. The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen. SRP. 2020; 11(1): 536-544. doi:10.5530/srp.2020.1.67 Vancouver/ICMJE Style Yusnidar Yusuf. The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen. SRP. (2020), [cited March 29, 2021]; 11(1): 536-544. doi:10.5530/srp.2020.1.67 Harvard Style Yusnidar Yusuf (2020) The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen. SRP, 11 (1), 536-544. doi:10.5530/srp.2020.1.67 Turabian Style Yusnidar Yusuf. 2020. The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen. Systematic Reviews in Pharmacy, 11 (1), 536-544. doi:10.5530/srp.2020.1.67 Chicago Style Yusnidar Yusuf. "The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen." Systematic Reviews in Pharmacy 11 (2020), 536-544. doi:10.5530/srp.2020.1.67 MLA (The Modern Language Association) Style Yusnidar Yusuf. "The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen." Systematic Reviews in Pharmacy 11.1 (2020), 536-544. Print. doi:10.5530/srp.2020.1.67 APA (American Psychological Association) Style Yusnidar Yusuf (2020) The Utilization of Laccase-Functionalized Graphene Oxide as an Effective Biodegradation of Pharmaceutical Industry Waste: Diclofenac and Ibuprofen. Systematic Reviews in Pharmacy, 11 (1), 536-544. doi:10.5530/srp.2020.1.67 |
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