Abstract

Hazima Mossa Alabassi, Zahraa Hussein M. Kadri, Maha A. Gathwan, Yasamine J. Kadem, Zahraa K. Kadhim

This investigation aims to shed light on the healing capability of Pimpkin (Cucurbita pepo L.) fruit on burn wounds, to do so thirty albino mice were separated into 3 groups: group one treated with cold extract, group two treated with hot extract and group three treated with ointment as control. Each group involved 10 mice, all animals were burned in femur by using solid aluminum bar, and the burned area was (8-10) mm in diameter with second degree burn. Hours after burning process, all animals treated with treatment as mention above (Twice/day) and during treatment; animals were sacrificed and histological study was performed. Result displayed that burn remedial was better among all animals treated with cold C. pepo extract comparing with burn-wound animals treated with hot C. pepo extract and ointment, by forming a thin epidermal layer. These result indicated the positive effect of pumpkin on wound healing. In conclusion it is the first time the therapeutic indication of the healing capability of cold C. pepo extract on burn wound, this open the door for clinical application of C. pepo fruit.