Hasan Dagli
Department of Medical Biochemistry, University of Kahramanmaras Sutcu Imam, Kahramanmaras, TurkeyPublications
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Research Article
Investigation of the Diagnostic and Prognostic Values of Some Specific microRNAs in Meningioma Tumors
Author(s): Hasan Dagli53921*, Özlem Gülbahar53922, Tuba Bulut53923, Mustafa Çağlar Şahin53924 and Ömer Hakan Emmez53925
Objective: Primary brain tumors are classified as glial or non-glial and benign or malignant. Meningiomas are common benign intracranial tumors. Although the name meningioma refers to a tumor of the lining of the brain called the ‘Meninx’, it has actually been shown to originate from the spider web-shaped ‘arachnoid’ membrane (arachnoid cover cells). microRNAs are 18- 22 nucleotide long, endogenous, non-protein-coding RNA molecules that negatively regulate gene expression at the post-transcriptional level. In this study, we applied a genome-wide array screen comparing the expression of miR-145, miR-34a-3p, miR-200a, miR- 335, miR-106a-5p, miR-219-5p, miR-375, miR-409-3p miR-197 and miR-224 in meningiomas. Materials and methods: A total of 40 meningioma patients (13 men, 27 women) and h.. Read More»
DOI: 10.31858/0975-8453.14.3.155-158
Abstract
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