Muhammad Tayyab

Department of Pharmaceutics, University of Karachi, Karachi, Pakistan

Publications

  • Research   
    Development and Evaluation of Co-Processed Excipient for Orally Dissolving Tablets
    Author(s): Muhammad Tayyab30246* and Muhammad Akram30247

    In this study, attempts were made on the design, development and evaluation of co-processed excipient that would be helpful in preparing Orally Dissolving Tablet. Co-processed excipient is mainly composed of known additives that are commonly used in the manufacturing of ODTs including mannitol, Microcrystalline Cellulose (MCC) and maize starch. Among different available techniques for co-processing, a more economical conventional technique was selected for the developing co-processed excipient consisting of excipient sizing, blending and physical agglomeration by wetting, wet screening, drying and followed by dry screening. Experiments were performed according to 32-level factorial design to observe the effect of two variables on critical quality attributes of co-processed excipient. The concentration of Microcrystalline Cellulose (X1) and maize starch (X2) were two numeric .. Read More»

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