Nikhitha K
Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research, Andhra Pradesh, IndiaPublications
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Research Article
Anti-Diarrheal Activity of Ethanolic Extract of Stylosanthes fruticosa Leaves in Mice
Author(s): Gayathri S49085*, Jayanth Reddy K49086, Samuel Y49099, Vyshnavi C49100, Savithri D49101, Pavithra H49102, Nikhitha K49103 and Soma Sekhar Reddy K49104
Stylosanthes fruticos, a perennial plant has been revered in ayurveda medicine for generations. The aim of the present study was to determine the antidiarrheal activity of ethanolic extract of S. fruticos (EESF), utilizing castor oil-induced, magnesium sulphate induced diarrhoea and castor oil-induced enteropooling in mice. The presence of alkaloids, carbohydrates, flavonoids, steroids, and phenols was discovered by phytochemical screening of EESF. At 25 mg/kg of dosage, the EESF provided considerable significant (p<0.05) inhibition on castor oil-induced diarrhea, magnesium sulphate induced diarrhea and castor oil induced enteropooling. From the findings, it was evident that EESF had dose-dependent antidiarrheal effects in all treatment groups, and the results were also well comparable with loperamide (3 mg/kg).. Read More»
DOI: 10.31858/0975-8453.14.1.6-10
Abstract
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