Rahangdale Priya
Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, IndiaPublications
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Research Article
Design, Synthesis and Pharmacological Screening of Novel Flavone Derivatives
Author(s): Sabale Prafulla31961*, Potey Lata31962, Sayyad Nusrat31963 and Rahangdale Priya31964
Flavonoids are the natural phytoconstituents widely distributed in plants originate in fruits, vegetables, grains, bark, roots, stems, flowers, tea and wine. Flavonoids have been recognized as secondary metabolites of plant, with marked biological significance such as Anti-inflammatory, Antioxidant, Anticancer and Antimicrobial activity. Hence, flavonoids are considered as an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications with versatile health benefits. Research on flavonoids received an added impulse with the discovery on Anti-inflammatory by several mechanisms, but the most important mechanism is the inhibition of eicosanoids generating enzyme. In present research a novel series of synthetic flavones (1a-l) have been synthesized after Molecular Docking studies. Synthesis of .. Read More»