Sabinus Oscar O. Eze

Department of Biochemistry, University of Nigeria, Nsukka, Nigeria

Publications

  • Review Article   
    Mechanism of Antibiotic Resistance by Protein Moonlighting
    Author(s): Ikeanyibe Nneoma Collette74880*, Sabinus Oscar O. Eze74881, Tobechukwu Christian Ezike74882 and Kingsley Ozioma Omeje74883

    Antibiotic resistance has become a major global health crisis, posing significant challenges in the treatment of bacterial infections. Most antibiotic resistance has emerged as a result of mutation or through the transfer of genetic material between microorganisms. Some studies on bacterial resistance have shown that there is a huge diversity of resistance mechanisms, with their distribution and interaction being mostly complex and unknown. However, various biochemical and physiological mechanisms are responsible for the development of antibiotic resistance. However, emerging evidence suggests that protein moonlighting, a phenomenon where a single protein can perform multiple functions in the cell beyond its originally described role, plays an important role in antibiotic resistance. Some proteins involved in the normal functioning of bacterial cells may have the ability to interact w.. Read More»
    DOI: 10.31858/0975-8453.15.9.283-286

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