Surbhi Chauhan

Department of Pharmacy, School of Allied Health Sciences and Management, Delhi Pharmaceutical Sciences and Research University, New Delhi, India

Publications

  • Research Article   
    Efficacy and Safety of mRNA based COVID-19 Vaccines: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
    Author(s): Neeru Chaudhary57763*, Rakhi Ahuja57764, Amena Sherwani57765 and Surbhi Chauhan57766

    Presently, evidence-based research studies on the efficacy and safety of mRNA COVID-19 vaccines are limited. The objective of this study is to conduct a systematic review and meta-analysis of Randomized Controlled Trials (RCTs) to learn about the efficacy of mRNA COVID-19 vaccines and the side effects associated with them. We used five databases to conduct an electronic search of material published between 2020 and June 2021. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) declaration was used to create and report on a procedure for a systematic review and meta-analysis. The systematic review comprised eleven RCTs, and nine RCTs were included for meta-analysis. To assess bias risk, the Cochrane collaboration tool was employed. In a total of 70604 cases, the overall effectiveness of the mRNA vaccines was determined to be 94.6% (95% CI 0.04-0.08). The adm.. Read More»
    DOI: 10.31858/0975-8453.14.5.301-305

    Abstract HTML PDF