Swathi Nalla

Department of Pharmacology, Maharajah’s College of Pharmacy, Vizianagaram, India

Publications

  • Review Article   
    An Overview on Biomarkers of Neurodegenerative Disease: Brain Aging
    Author(s): Swathi Nalla58952* and Ganta Suhasin58953

    Brain aging is a neurodegenerative disorder, whose prevalence has increased worldwide. According to World Health Organization (WHO) guidelines, dementia due to neurodegenerative disorder is 22%, i.e., ≥ 80 million people among the world’s population are affected by aging. According to a survey in 2010, 8% of the Indian population was affected by aging, which may reach 19% by 2050. Neurodegenerative damage contributes to persistent diseases such as Alzheimer’s disease, Parkinson’s disease and stroke in the aging brain. Functional impairment in cognition is mainly due to the formation of Amyloid beta (Aβ) plaques and neurofibrillary tangles in the brain. The main causes of brain aging are the generation and accumulation of free radicals, i.e., Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS), gene regulation, mitochondrial dysfunction, apoptosi.. Read More»
    DOI: 10.31858/0975-8453.14.6.383-392

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